SCHEMBL36017

SCHEMBL36017

O=C(O)c1ccc(-c2ccccc2-c2ccccc2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.59
DAO P14920 1/20 0.59
NAPRT Q6XQN6 1/20 0.59
EGFR P00533 1/20 0.59
TP53 P04637 1/20 0.57
NPC1 O15118 1/20 0.57
RAB9A P51151 1/20 0.57
SRD5A2 P31213 3/20 0.56
CES2 O00748 1/20 0.56
CES1 P23141 1/20 0.56
RXRA P19793 2/20 0.56
RXRB P28702 1/20 0.56
RXRG P48443 1/20 0.56
RARB P10826 1/20 0.56
RARG P13631 1/20 0.56
MAP4K4 O95819 1/20 0.54
BCL2L1 Q07817 1/20 0.52
BAD Q92934 1/20 0.52
MAPT P10636 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28397371 0.98 EGFR (0.62) TSHRDAONAPRTEGFRTP53
SCHEMBL25390971 0.98 TSHR (0.62) TSHRDAONAPRTEGFRTP53
SCHEMBL31236746 0.95 TSHR (0.59) TSHRDAONAPRTEGFRTP53
SCHEMBL31327313 0.95 TSHR (0.59) TSHRDAONAPRTEGFRTP53
SCHEMBL8923959 0.89 CA12 (0.67) TSHRDAONAPRTEGFRTP53
SCHEMBL17014850 0.88 EGFR (0.62) TSHRDAONAPRTEGFRTP53
Biphenyl SCHEMBL5186249 0.87 EGFR (0.72) TSHRDAONAPRTEGFRTP53
Terephthalic Acid SCHEMBL10780545 0.87 EGFR (0.72) TSHRDAONAPRTEGFRTP53
SCHEMBL7155730 0.87 EGFR (0.72) TSHRDAONAPRTEGFRTP53
SCHEMBL38562 0.87 EGFR (0.72) TSHRDAONAPRTEGFRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117142703-A Carbon reduction zero emission method and system for p-carboxyl-containing terphenyl sewage 华润化学材料科技股份有限公司 2023-12-01 CN claimed
CN-113957094-B Delivery system with enhanced gene editing efficiency, preparation method and application 华中科技大学同济医学院附属协和医院 2023-11-21 CN claimed
CN-113788955-B Metal organic framework catalyst, preparation method and application 华中科技大学同济医学院附属协和医院 2022-09-23 CN claimed
CN-101484410-A Terphenyl derivatives for treatment of alzheimer's disease ORTHO MCNEIL JANSSEN PHARM (US) 2009-07-15 CN claimed
CN-101218201-A Benzoic acid derivatives as GlyR modulators or agonists ASTRAZENECA AB (SE) 2008-07-09 CN claimed
EP-1635829-A1 8-(3-BIARYL)PHENYLQUINOLINE PHOSPHODIESTERASE-4-INHIBITORS Merck Frosst Canada Ltd. (CA) 2006-03-22 EP claimed
WO-2004096220-A1 8-(3-BIARYL)PHENYLQUINOLINE PHOSPHODIESTERASE-4-INHIBITORS MERCK FROSST CANADA LTD. (CA) 2004-11-11 WO claimed
CN-1308604-A 2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia AMERICAN HOME PROD (US) 2001-08-15 CN claimed
CN-117142703-A Carbon reduction zero emission method and system for p-carboxyl-containing terphenyl sewage 华润化学材料科技股份有限公司 2023-12-01 CN disclosed
CN-113957094-B Delivery system with enhanced gene editing efficiency, preparation method and application 华中科技大学同济医学院附属协和医院 2023-11-21 CN disclosed
CN-113788955-B Metal organic framework catalyst, preparation method and application 华中科技大学同济医学院附属协和医院 2022-09-23 CN disclosed
CN-113788955-B Metal organic framework catalyst, preparation method and application 华中科技大学同济医学院附属协和医院 2022-09-23 CN disclosed
CN-111337466-A Method for manufacturing metal-organic framework fluorescent material detection test strip for ultra-fast on-site detection of parathion 浙江省农业科学院 2020-06-26 CN disclosed
CN-104250214-B Polymerizable compounds and their use in liquid crystal displays 默克专利股份有限公司 2018-10-19 CN disclosed
US-6252624-B1 Three dimensional display IDEMITSU KOSAN CO., LTD. (JP) 2001-06-26 US disclosed
CN-1216980-A Triaryl compounds NOVARTIS AG (CH) 1999-05-19 CN disclosed
EP-0892563-A2 Stereoscopic television system IDEMITSU KOSAN CO., LTD. (JP) 1999-01-20 EP disclosed
US-4777300-A Aromatic ketone IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-10-11 US disclosed
EP-0232992-A1 Aromatic ketone IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-08-19 EP disclosed
US-4154922-A PLASTICIZERS FOR PVC STANDARD OIL COMPANY (INDIANA) (US) 1979-05-15 US disclosed