SCHEMBL8923959

SCHEMBL8923959

O=C(O)c1ccc(-c2ccccc2-c2ccc(O)cc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.67
CA1 P00915 1/20 0.67
CA2 P00918 1/20 0.67
CA3 P07451 1/20 0.67
TYR P14679 1/20 0.67
DRD1 P21728 1/20 0.67
CA4 P22748 1/20 0.67
CA6 P23280 1/20 0.67
CA5A P35218 1/20 0.67
CA7 P43166 1/20 0.67
CA9 Q16790 1/20 0.67
CA14 Q9ULX7 1/20 0.67
CA5B Q9Y2D0 1/20 0.67
SRD5A2 P31213 2/20 0.59
MEN1 O00255 1/20 0.59
LMNA P02545 1/20 0.59
MAPT P10636 1/20 0.59
RAB9A P51151 1/20 0.59
KMT2A Q03164 1/20 0.59
EGFR P00533 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25390971 0.91 TSHR (0.62) CA12CA1CA2CA9SRD5A2
SCHEMBL31236746 0.89 TSHR (0.59) CA12CA1CA2CA9SRD5A2
SCHEMBL31327313 0.89 TSHR (0.59) CA12CA1CA2CA9SRD5A2
SCHEMBL36017 0.89 TSHR (0.59) CA12CA1CA2CA9SRD5A2
Terephthalic Acid SCHEMBL9189723 0.87 EGFR (0.74) CA12CA1CA2CA3TYR
Paraben SCHEMBL8089146 0.87 EGFR (0.74) CA12CA1CA2CA3TYR
Terephthalic Acid SCHEMBL10442831 0.87 EGFR (0.74) CA12CA1CA2CA3TYR
SCHEMBL5710458 0.87 EGFR (0.74) CA12CA1CA2CA3TYR
SCHEMBL28397371 0.87 EGFR (0.62) SRD5A2MAPTRAB9AEGFRCES2
2-Phenylphenol SCHEMBL27898045 0.86 BCL2L1 (0.63) CA12CA1CA2CA3TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5658493-A Ferroelectric liquid crystals for nonlinear optics applications UNIVERSITY RESEARCH CORPORATION (US) 1997-08-19 US disclosed
US-5637256-A Ferroelectric liquid crystals for nonlinear optics applications UNIVERSITY RESEARCH CORPORATION (US) 1997-06-10 US disclosed
US-5543078-A A CHIRAL NONRACEMIC COMPOUND UNIVERSITY RESEARCH CORPORATION (US) 1996-08-06 US disclosed
WO-1992020058-A2 FERROELECTRIC LIQUID CRYSTALS FOR NONLINEAR OPTICS APPLICATIONS UNIVERSITY RESEARCH CORPORATION (US) 1992-11-12 WO disclosed