Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 12/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8002319 | 0.74 | MGLL (0.67) | MGLLTDP1ALDH1A1HSP90AA1PKM | |
| SCHEMBL13056396 | 0.73 | TLR9 (0.74) | TLR9MGLLTDP1ALDH1A1HSP90AA1 | |
| SCHEMBL9171144 | 0.71 | MGLL (0.50) | MGLLALDH1A1HSP90AA1PKMATM | |
| Benzaldehyde SCHEMBL7538689 | 0.70 | ALDH1A1 (0.56) | ALDH1A1PKMKMT2AHTT | |
| SCHEMBL585297 | 0.70 | TLR9 (0.61) | TLR9MGLLTDP1ALDH1A1HSP90AA1 | |
| SCHEMBL8761207 | 0.68 | NR1H3 (0.41) | TDP1MEN1KMT2ALMNATHRB | |
| SCHEMBL121404 | 0.68 | TLR9 (1.00) | TLR9MGLLTDP1ALDH1A1HSP90AA1 | |
| SCHEMBL29377102 | 0.68 | TLR9 (1.00) | TLR9MGLLTDP1ALDH1A1HSP90AA1 | |
| SCHEMBL23142679 | 0.66 | NR1H3 (0.62) | TDP1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL1193709 | 0.66 | TLR9 (0.51) | TLR9MGLLTDP1ALDH1A1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4490173-A1 | IMMUNOMODULATORY PROTEINS OF VARIANT CD80 POLYPEPTIDES, CELL THERAPIES THEREOF AND RELATED METHODS AND USES | Alpine Immune Sciences, Inc. (US) | 2025-01-15 | — | — | EP | disclosed |
| WO-2023172883-A1 | IMMUNOMODULATORY PROTEINS OF VARIANT CD80 POLYPEPTIDES, CELL THERAPIES THEREOF AND RELATED METHODS AND USES | ALPINE IMMUNE SCIENCES, INC. (US) | 2023-09-14 | — | — | WO | disclosed |