Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.58 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.54 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20758445 | 0.90 | GPR119 (0.60) | GPR119CHEK2ALOX5APFEN1BACE1 | |
| SCHEMBL31752479 | 0.87 | CHEK2 (0.56) | GPR119CHEK2 | |
| SCHEMBL31752455 | 0.85 | GPR119 (0.56) | GPR119CHEK2 | |
| SCHEMBL1646632 | 0.83 | GPR119 (0.59) | GPR119CHEK2 | |
| SCHEMBL30643608 | 0.83 | ALOX5AP (0.49) | GPR119ALOX5APFEN1BACE1 | |
| SCHEMBL25209637 | 0.83 | GPR4 (0.49) | GPR119 | |
| SCHEMBL25396123 | 0.83 | GPR119 (0.57) | GPR119CHEK2 | |
| SCHEMBL2488375 | 0.83 | GPR119 (0.56) | GPR119CHEK2BACE1 | |
| SCHEMBL14297532 | 0.83 | GPR119 (0.69) | GPR119 | |
| SCHEMBL13335340 | 0.82 | GPR119 (0.70) | GPR119CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220640-A1 | CDK PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023177356-A2 | COMPOUNDS AND METHOD FOR PKMYT1 INHIBITION | ENGINE BIOSCIENCES PTE. LTD. (SG) | 2023-09-21 | — | — | WO | disclosed |