SCHEMBL2539722

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14286188	0.86	KDM4E (1.00)	KDM4ECYP3A4CYP2C19HIF1AALDH1A1
	SCHEMBL2540087	0.85	KDM4E (0.78)	KDM4ECYP3A4CYP2C19HIF1AALDH1A1
	SCHEMBL2534945	0.83	CYP3A4 (0.76)	KDM4ECYP3A4CYP2C19HIF1AALDH1A1
	SCHEMBL12638631	0.83	CYP1A2 (0.52)	KDM4ECYP3A4CYP2C19HIF1AALDH1A1
	SCHEMBL1599148	0.83	KDM4E (0.51)	KDM4ECYP3A4CYP2C19HIF1AALDH1A1
	SCHEMBL9724241	0.81	KDM4E (0.50)	KDM4ECYP3A4CYP2C19HIF1AALDH1A1
	SCHEMBL2537741	0.81	CYP3A4 (0.71)	KDM4ECYP3A4CYP2C19HIF1AALDH1A1
	SCHEMBL9724194	0.80	KDM4E (0.49)	KDM4ECYP3A4CYP2C19HIF1AALDH1A1
	SCHEMBL7059976	0.78	KDM4E (0.68)	KDM4ECYP3A4CYP2C19HIF1AMAPT
	SCHEMBL1223950	0.77	CYP2C19 (0.62)	KDM4ECYP3A4CYP2C19HIF1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.