SCHEMBL2534945

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30908484	0.87	KDM4E (0.57)	CYP3A4KDM4ECYP2C19HIF1AHSD17B10
	SCHEMBL14286188	0.86	KDM4E (1.00)	CYP3A4KDM4ECYP2C19HIF1AHSD17B10
	SCHEMBL2540087	0.85	KDM4E (0.78)	CYP3A4KDM4ECYP2C19HIF1AHSD17B10
	SCHEMBL2539722	0.83	KDM4E (0.76)	CYP3A4KDM4ECYP2C19HIF1AHSD17B10
	SCHEMBL2537741	0.81	CYP3A4 (0.71)	CYP3A4KDM4ECYP2C19HIF1AHSD17B10
	SCHEMBL7059976	0.78	KDM4E (0.68)	CYP3A4KDM4ECYP2C19HIF1AMAPT
	SCHEMBL2535691	0.77	KDM4E (0.62)	CYP3A4KDM4ECYP2C19HIF1AHSD17B10
	SCHEMBL7051543	0.77	KDM4E (0.66)	CYP3A4KDM4ECYP2C19HIF1AHSD17B10
	SCHEMBL2538787	0.77	KDM4E (0.66)	CYP3A4KDM4ECYP2C19HIF1AALDH1A1
	SCHEMBL2538783	0.77	KDM4E (0.66)	CYP3A4KDM4ECYP2C19HIF1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.