Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ESRRG | P62508 | 4/20 | 0.51 |
| ▸ | KDM1A | O60341 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8290617 | 0.81 | ALDH1A1 (0.73) | KMT2AMEN1ALDH1A1POLBGAA | |
| SCHEMBL266582 | 0.75 | PKM (0.62) | KMT2AMEN1ALDH1A1POLBGAA | |
| SCHEMBL266583 | 0.75 | PKM (0.62) | KMT2AMEN1ALDH1A1POLBGAA | |
| SCHEMBL2538234 | 0.75 | KMT2A (0.60) | KMT2AMEN1ALDH1A1POLBGAA | |
| SCHEMBL7715528 | 0.74 | KDM1A (0.39) | KMT2AMEN1ALDH1A1POLBGAA | |
| SCHEMBL7715533 | 0.74 | KDM1A (0.39) | KMT2AMEN1ALDH1A1POLBGAA | |
| SCHEMBL7715531 | 0.74 | KDM1A (0.39) | KMT2AMEN1ALDH1A1POLBGAA | |
| SCHEMBL8291229 | 0.74 | POLB (0.60) | KMT2AMEN1ALDH1A1POLBGAA | |
| SCHEMBL19283332 | 0.73 | KDM1A (0.74) | KMT2AMEN1POLBMAPTSMN1; SMN2 | |
| SCHEMBL19283331 | 0.73 | KDM1A (0.74) | KMT2AMEN1POLBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044241-B2 | Ligands for estrogen related receptors and methods for synthesis of said ligands | CITY OF HOPE (US) | 2011-10-25 | — | — | US | disclosed |