Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25398117 | 1.00 | AAK1 (0.36) | AAK1IRAK4ALDH1A1GAA | |
| SCHEMBL25399501 | 0.82 | ALDH1A1 (0.44) | IRAK4ALDH1A1GAA | |
| SCHEMBL25399497 | 0.82 | ALDH1A1 (0.44) | IRAK4ALDH1A1GAA | |
| SCHEMBL25394462 | 0.71 | SCN4A (0.41) | ALDH1A1GAA | |
| SCHEMBL25394459 | 0.71 | SCN4A (0.41) | ALDH1A1GAA | |
| SCHEMBL23301644 | 0.69 | NR4A2 (0.53) | — | |
| SCHEMBL4524906 | 0.69 | NR3C1 (0.52) | — | |
| SCHEMBL25398262 | 0.69 | ALDH1A1 (0.42) | ALDH1A1GAA | |
| SCHEMBL25398255 | 0.69 | ALDH1A1 (0.42) | ALDH1A1GAA | |
| SCHEMBL25398313 | 0.65 | ALDH1A1 (0.47) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250213571-A1 | TYK2 INHIBITORS AND USES THEREOF | ALUMIS INC. | 2025-07-03 | — | — | US | disclosed |
| EP-4493562-A1 | TYK2 INHIBITORS AND USES THEREOF | Alumis Inc. (US) | 2025-01-22 | — | — | EP | disclosed |
| WO-2023178235-A1 | TYK2 INHIBITORS AND USES THEREOF | ALUMIS INC. (US) | 2023-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250213571-A1 | TYK2 INHIBITORS AND USES THEREOF | TYK2, JAK1, JAK2 | AAK1 92/4885IRAK4 17/4885ALDH1A1 4098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.