Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | PLAU | P00749 | 2/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL261742 | 0.87 | ATR (0.54) | NPSR1ATRGRM5KDM4EALDH1A1 | |
| SCHEMBL30050535 | 0.87 | ATR (0.54) | NPSR1ATRGRM5KDM4EALDH1A1 | |
| SCHEMBL30570809 | 0.85 | NPSR1 (0.56) | NPSR1ATRGRM5KDM4EALDH1A1 | |
| SCHEMBL361309 | 0.84 | NPSR1 (0.45) | NPSR1ATRKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1680511 | 0.84 | PLAU (0.53) | NPSR1KDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL29483844 | 0.82 | NPSR1 (0.47) | NPSR1ATRKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL22439886 | 0.82 | NPSR1 (0.47) | NPSR1ATRKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12248189 | 0.82 | NPSR1 (0.47) | NPSR1GRM5KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28058779 | 0.81 | ATR (0.36) | ATRGRM5KDM4EALDH1A1HPGD | |
| SCHEMBL29410004 | 0.81 | NPSR1 (0.45) | NPSR1GRM5KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250188059-A1 | NOVEL COMPOUND AND USE THEREOF FOR INHIBITING CHECKPOINT KINASE 2 | ARUM THERAPEUTICS INC (KR) | 2025-06-12 | — | — | US | disclosed |
| EP-4495111-A1 | NOVEL COMPOUND AND USE THEREOF FOR INHIBITING CHECKPOINT KINASE 2 | Arum Therapeutics Inc (KR) | 2025-01-22 | — | — | EP | disclosed |
| CN-118891255-A | Novel compounds and their use for inhibiting checkpoint kinase 2 | 阿鲁姆治疗公司 | 2024-11-01 | — | — | CN | disclosed |
| WO-2023177233-A1 | NOVEL COMPOUND AND USE THEREOF FOR INHIBITING CHECKPOINT KINASE 2 | (주)아름테라퓨틱스 | 2023-09-21 | — | — | WO | disclosed |
| CN-106866553-B | Synthesis method of Favipiravir | 中南大学 | 2020-02-04 | — | — | CN | disclosed |
| CN-106866553-A | A kind of synthetic method of Favipiravir | 中南大学 | 2017-06-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250188059-A1 | NOVEL COMPOUND AND USE THEREOF FOR INHIBITING CHECKPOINT KINASE 2 | CHEK2, CHEK1, PARP2 | NPSR1 4628/4885ATR 29/4885GRM5 4095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.