Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL260853 | 1.00 | NPSR1 (0.45) | NPSR1KDM4EPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL29844710 | 0.88 | GRM5 (0.52) | NPSR1KDM4EPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL261816 | 0.88 | GRM5 (0.52) | NPSR1KDM4EPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL20046668 | 0.84 | NPSR1 (0.56) | NPSR1KDM4EPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL1680511 | 0.82 | PLAU (0.53) | NPSR1KDM4EPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL4014560 | 0.82 | NPSR1 (0.48) | NPSR1KDM4EPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL29585697 | 0.82 | NPSR1 (0.48) | NPSR1KDM4EPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL25399004 | 0.81 | NPSR1 (0.47) | NPSR1KDM4EPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL361753 | 0.81 | NPSR1 (0.47) | NPSR1KDM4EPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL12248189 | 0.81 | NPSR1 (0.47) | NPSR1KDM4EPKMALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3968983-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | F. Hoffmann-La Roche AG (CH) | 2022-03-23 | — | — | EP | disclosed |