SCHEMBL25399055

SCHEMBL25399055

Cn1nc(OC(N)=O)cc1C(F)(F)F

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.60
NPC1 O15118 2/20 0.59
RAB9A P51151 1/20 0.58
MAPT P10636 5/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
NPSR1 Q6W5P4 1/20 0.56
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
ALDH1A1 P00352 1/20 0.40
KIF11 P52732 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.36
GAA P10253 2/20 0.36
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33
HCRTR2 O43614 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27989450 0.78 NPC1 (0.67) PKMNPC1RAB9AMAPTSMN1; SMN2
SCHEMBL8111889 0.78 PKM (0.55) PKMNPC1RAB9AMAPTSMN1; SMN2
SCHEMBL27814622 0.77 PKM (0.52) PKMNPC1RAB9AMAPTSMN1; SMN2
SCHEMBL3382600 0.75 PKM (0.57) PKMNPC1RAB9AMAPTSMN1; SMN2
SCHEMBL20798394 0.75 PKM (1.00) PKMNPC1RAB9AMAPTSMN1; SMN2
SCHEMBL27854791 0.75 NPC1 (1.00) PKMNPC1RAB9AMAPTSMN1; SMN2
SCHEMBL28490230 0.75 NPC1 (0.34) PKMNPC1RAB9AMAPTSMN1; SMN2
SCHEMBL17940 0.75 PKM (0.49) PKMNPC1RAB9AMAPTSMN1; SMN2
SCHEMBL8086287 0.72 PKM (0.34) PKMNPC1RAB9AMAPTSMN1; SMN2
SCHEMBL28711180 0.72 NPC1 (0.33) PKMNPC1RAB9AMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023171665-A1 PIPERIDINONE DERIVATIVE OR SALT THEREOF, HARMFUL ORGANISM CONTROL AGENT CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME 株式会社ADEKA 2023-09-14 WO disclosed