Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28689825 | 0.80 | FAAH (0.33) | PKMNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL28490230 | 0.76 | NPC1 (0.34) | PKMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6825782 | 0.74 | PLA2G10 (0.45) | MAPTNPSR1 | |
| SCHEMBL28711180 | 0.73 | NPC1 (0.33) | PKMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL25399055 | 0.72 | PKM (0.60) | PKMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL28545542 | 0.72 | NPC1 (0.35) | PKMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL28695273 | 0.69 | — | — | |
| SCHEMBL28690905 | 0.67 | NPC1 (0.34) | PKMNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL28560051 | 0.67 | CYP11B2 (0.32) | — | |
| SCHEMBL29680611 | 0.67 | MALT1 (0.38) | NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051431-A1 | THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037668-A1 | THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1999-07-29 | — | — | WO | disclosed |