SCHEMBL25399165

SCHEMBL25399165

CCCCCCCCCCCCCCCCCCN(C1CCCCC1)C1CCCCC1

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.49
THRB P10828 1/20 0.49
ADH1A P07327 4/20 0.46
ADH1C P00326 3/20 0.46
ADH4 P08319 1/20 0.46
CYP1A2 P05177 1/20 0.41
DNM1 Q05193 3/20 0.41
SIGMAR1 Q99720 3/20 0.39
NAAA Q02083 2/20 0.38
EPHX1 P07099 4/20 0.36
EPHX2 P34913 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14199746 1.00 THRA (0.49) THRATHRBADH1AADH1CADH4
SCHEMBL4945132 1.00 THRA (0.49) THRATHRBADH1AADH1CADH4
SCHEMBL11351005 1.00 THRA (0.49) THRATHRBADH1AADH1CADH4
SCHEMBL11200486 1.00 THRA (0.49) THRATHRBADH1AADH1CADH4
SCHEMBL39006 1.00 THRA (0.49) THRATHRBADH1AADH1CADH4
SCHEMBL11344593 1.00 THRA (0.49) THRATHRBADH1AADH1CADH4
SCHEMBL39346 1.00 THRA (0.49) THRATHRBADH1AADH1CADH4
SCHEMBL11210017 1.00 THRA (0.49) THRATHRBADH1AADH1CADH4
SCHEMBL14199743 0.98 THRA (0.47) THRATHRBADH1AADH1CADH4
SCHEMBL9177788 0.98 ADH1A (0.47) THRATHRBADH1AADH1CADH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11738487-B2 Processes for making molded flexible foams and flexible foams produced thereby COVESTRO LLC (US) 2023-08-29 US disclosed
CN-114805727-A Process for preparing molded flexible foams and flexible foams prepared therefrom 科思创有限公司 2022-07-29 CN disclosed
US-20220235168-A1 PROCESSES FOR MAKING MOLDED FLEXIBLE FOAMS AND FLEXIBLE FOAMS PRODUCED THEREBY COVESTRO LLC 2022-07-28 US disclosed
US-20220234262-A1 PROCESSES FOR MAKING MOLDED FLEXIBLE FOAMS AND FLEXIBLE FOAMS PRODUCED THEREBY COVESTRO LLC 2022-07-28 US disclosed
EP-4032926-A1 PROCESSES FOR MAKING MOLDED FLEXIBLE FOAMS AND FLEXIBLE FOAMS PRODUCED THEREBY Covestro LLC (US) 2022-07-27 EP disclosed
EP-4032925-A1 PROCESSES FOR MAKING MOLDED FLEXIBLE FOAMS AND FLEXIBLE FOAMS PRODUCED THEREBY Covestro LLC (US) 2022-07-27 EP disclosed
CN-114773561-A Process for producing molded flexible foam and flexible foam produced by the process 科思创有限公司 2022-07-22 CN disclosed