Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1021170 | 0.86 | LTA4H (0.59) | LTA4HPTGS1PTGS2HRH3MEN1 | |
| SCHEMBL6413519 | 0.85 | LTA4H (0.58) | LTA4HPTGS1PTGS2HRH3HTR2A | |
| Hydrochloric Acid SCHEMBL1640534 | 0.85 | LTA4H (0.58) | LTA4HPTGS1PTGS2HRH3MEN1 | |
| SCHEMBL3388992 | 0.84 | LTA4H (0.47) | LTA4HPTGS1PTGS2HRH3MEN1 | |
| SCHEMBL55617 | 0.82 | SIGMAR1 (0.48) | LTA4HSIGMAR1KDM4E | |
| SCHEMBL15651242 | 0.82 | LTA4H (0.46) | LTA4HPTGS1PTGS2HRH3MEN1 | |
| SCHEMBL29769807 | 0.82 | SIGMAR1 (0.48) | LTA4HSIGMAR1KDM4E | |
| Hydrochloric Acid SCHEMBL16210022 | 0.81 | NPC1 (0.48) | LTA4HSIGMAR1KDM4E | |
| SCHEMBL16973077 | 0.80 | LTA4H (0.44) | LTA4HPTGS1PTGS2HRH3MEN1 | |
| SCHEMBL12156614 | 0.78 | LTA4H (0.67) | LTA4HPTGS1PTGS2HRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023177356-A2 | COMPOUNDS AND METHOD FOR PKMYT1 INHIBITION | ENGINE BIOSCIENCES PTE. LTD. (SG) | 2023-09-21 | — | — | WO | disclosed |
| WO-2023177356-A2 | COMPOUNDS AND METHOD FOR PKMYT1 INHIBITION | ENGINE BIOSCIENCES PTE. LTD. (SG) | 2023-09-21 | — | — | WO | disclosed |