Sugi Predict

Sugi Predict / Compounds / SCHEMBL25401040

SCHEMBL25401040

SCHEMBL25401040

O=C(O)c1ccc2nn(Cc3cc(F)cc(F)c3)cc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HDAC6 Q9UBN7 2/20 0.41
▸ P2RY14 Q15391 1/20 0.41
▸ HDAC1 Q13547 1/20 0.39
▸ HSD17B10 Q99714 1/20 0.38
▸ HDAC2 Q92769 1/20 0.38
▸ NR4A2 P43354 1/20 0.38
▸ AGTR1 P30556 1/20 0.38
▸ AGTR2 P50052 1/20 0.38
▸ NPC1 O15118 2/20 0.38
▸ RAB9A P51151 2/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ KDM4C Q9H3R0 2/20 0.37
▸ ENPP2 Q13822 1/20 0.37
▸ PTGER4 P35408 2/20 0.37
▸ PTGER2 P43116 1/20 0.37
▸ TDP1 Q9NUW8 2/20 0.37
▸ POLB P06746 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6840441 0.90 KDM5A (0.47) HDAC6P2RY14HDAC1HSD17B10NR4A2
SCHEMBL31632979 0.89 KDM4C (0.50) P2RY14NR4A2NPC1RAB9AKDM4C
SCHEMBL23632217 0.87 AGTR1 (0.50) HDAC6HDAC1HSD17B10AGTR1AGTR2
SCHEMBL25402598 0.85 HTT (0.43) HDAC6HSD17B10HDAC2RAB9AMEN1
SCHEMBL25402755 0.85 HCAR3 (0.49) HDAC6HSD17B10HDAC2NPC1RAB9A
SCHEMBL25402055 0.83 HDAC6 (0.59) HDAC6HSD17B10NR4A2NPC1RAB9A
SCHEMBL6840368 0.82 KDM4E (0.47) HDAC6P2RY14HSD17B10HDAC2NPC1
SCHEMBL25402226 0.82 HDAC6 (0.49) HDAC6HDAC1HSD17B10HDAC2MEN1
SCHEMBL6844901 0.81 PTGER4 (0.46) HDAC6P2RY14HDAC1PTGER4
SCHEMBL25404873 0.81 EGLN1 (0.50) HDAC6HDAC1HSD17B10HDAC2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250197369-A1 NOVEL HETEROCYCLIC INHIBITOR FOR HISTONE DEACETYLASE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME SOOKMYUNG WOMEN'S UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2025-06-19 — — US disclosed
EP-4494640-A1 NOVEL HETEROCYCLIC INHIBITOR FOR HISTONE DEACETYLASE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Sookmyung Women's University Industry-Academic Cooperation Foundation (KR) 2025-01-22 — — EP disclosed
CN-119212701-A Novel histone deacetylase heterocycle inhibitor and pharmaceutical composition containing the same 淑明女子大学校 产学协力团 2024-12-27 — — CN disclosed
WO-2023177250-A1 NOVEL HETEROCYCLIC INHIBITOR FOR HISTONE DEACETYLASE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 숙명여자대학교산학협력단 2023-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250197369-A1 NOVEL HETEROCYCLIC INHIBITOR FOR HISTONE DEACETYLASE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME HDAC1, HDAC6, HDAC5 HDAC6 2/4885P2RY14 4396/4885HDAC1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.