Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6029391 | 0.88 | ALDH1A1 (0.52) | PARP1MYCALDH1A1HPGDKDM4E | |
| SCHEMBL11245121 | 0.88 | ALDH1A1 (0.57) | MYCALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL311565 | 0.86 | PARP1 (0.46) | PARP1MYCALDH1A1HPGDKDM4E | |
| SCHEMBL5742619 | 0.84 | MYC (0.53) | PARP1MYCALDH1A1HPGDKDM4E | |
| SCHEMBL466296 | 0.84 | KDM4E (0.54) | PARP1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL11559840 | 0.83 | P2RX7 (0.45) | PARP1MYCALDH1A1HPGDKDM4E | |
| SCHEMBL7457386 | 0.83 | PLK1 (0.43) | PARP1MYCALDH1A1HPGDKDM4E | |
| SCHEMBL4621991 | 0.83 | PLK1 (0.47) | MYCALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL29025210 | 0.81 | ALDH1A1 (0.42) | PARP1MYCALDH1A1HPGDKDM4E | |
| SCHEMBL2466290 | 0.81 | CLCN2 (0.51) | PARP1MYCALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2874808-B1 | METHOD FOR CONTINUOUS PRODUCTION OF FOAMS IN PIPES | BASF SE (DE) | 2016-11-16 | — | — | EP | claimed |
| US-20140020784-A1 | PROCESS FOR THE CONTINUOUS PRODUCTION OF FOAMS IN PIPES | BASF SE (DE) | 2014-01-23 | — | — | US | claimed |
| EP-1732896-B1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | AVENTIS PHARMA INC (US) | 2012-12-12 | — | — | EP | claimed |
| US-20120202795-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | AVENTIS PHARMACEUTICALS INC. (US) | 2012-08-09 | — | — | US | claimed |
| CN-101253167-A | Substituted imidazole compounds as KSP inhibitors | NOVARTIS VACCINES & DIAGNOSTIC (CH) | 2008-08-27 | — | — | CN | claimed |
| WO-2008007979-A1 | (2,6-DIOXO-3-PIPERINYL)AMIDOBENZOIC IMMUNOMODULATORY AND ANTI-CANCER DERIVATIVES | AUCKLAND UNISERVICES LIMITED (NZ) | 2008-01-17 | — | — | WO | claimed |
| US-20070032489-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | AVENTIS PHARMACEUTICALS INC. (US) | 2007-02-08 | — | — | US | claimed |
| EP-1732896-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | Aventis Pharmaceuticals Inc. (US) | 2006-12-20 | — | — | EP | claimed |
| WO-2005097750-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | AVENTIS PHARMACEUTICALS INC. (US) | 2005-10-20 | — | — | WO | claimed |
| WO-2002020437-A2 | BASIC COMPOUNDS CONTAINING TERTIARY AMIDES WITH ACTIVITY ON TACHYKININ RECEPTORS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MENARINI RICERCHE S.P.A. (IT) | 2002-03-14 | — | — | WO | claimed |
| CN-119080900-A | Scorpion toxin mutant ChTX-Q18W and application thereof in preparation of antiepileptic drugs | 中国科学院上海有机化学研究所 | 2024-12-06 | — | — | CN | disclosed |
| US-11982395-B2 | Insulated pipe containing polyurethane foam which is foamed by an environmentally friendly foaming agent and has a low degree of brittleness | BASF SE (DE) | 2024-05-14 | — | — | US | disclosed |
| CN-113122566-B | Role of HAK gene in regulating and controlling plant traits | 山东舜丰生物科技有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-115710307-A | Application of scorpion toxin and mutant thereof in resisting epilepsy | 中国科学院上海有机化学研究所 | 2023-02-24 | — | — | CN | disclosed |
| CN-113242906-B | Application of TPST gene in regulation and control of plant traits | 山东舜丰生物科技有限公司 | 2022-12-23 | — | — | CN | disclosed |
| US-4835312-A | Production process of N-substituted amide compounds | MITSUI CHEMICALS, INCORPORATED (JP) | 1989-05-30 | — | — | US | disclosed |
| EP-0180141-A1 | Process for making diene polymer rubbers | NIPPON ZEON CO., LTD. (JP) | 1986-05-07 | — | — | EP | disclosed |
| EP-0150479-A2 | Process for modifying conjugated diene polymers | NIPPON ZEON CO., LTD. (JP) | 1985-08-07 | — | — | EP | disclosed |
| US-4415745-A | AMMOXIDATION OF AN ALKYLATED AROMATIC TO A NITRILE; HYDROLYSIS TO AN AMIDE; REARRANGEMENT TO A CARBAMATE; ALDEHYDE CONDENSATION; NONTOXIC | EXXON RESEARCH & ENGINEERING CO. (US) | 1983-11-15 | — | — | US | disclosed |
| US-4321402-A | Carbamate process | EXXON RESEARCH & ENGINEERING CO. (US) | 1982-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202795-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | PARP1, PARP2, PARP3 | PARP1 1/4885MYC 4027/4885ALDH1A1 280/4885 |
| US-20070032489-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | PARP1, PARP2, PARP3 | PARP1 1/4885MYC 4027/4885ALDH1A1 280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.