Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2540281 | 1.00 | USP30 (0.35) | USP30PDE5AHTR2CPIN1ERN1 | |
| SCHEMBL12994249 | 0.87 | HTR2C (0.41) | USP30PDE5AHTR2CADRA1AALOX5AP | |
| SCHEMBL425810 | 0.85 | KDM1A (0.34) | JAK2JAK1TYK2JAK3HCRTR2 | |
| SCHEMBL1574664 | 0.85 | KDM1A (0.34) | JAK2JAK1TYK2JAK3HCRTR2 | |
| SCHEMBL4549748 | 0.85 | ALDH1A1 (0.35) | USP30PDE5AHTR2CADRA1AALOX5AP | |
| SCHEMBL12716293 | 0.85 | ALDH1A1 (0.35) | USP30PDE5AHTR2CADRA1AALOX5AP | |
| SCHEMBL803246 | 0.84 | HTR2C (0.33) | USP30PDE5AHTR2CADRA1AALOX5AP | |
| SCHEMBL4549750 | 0.84 | HTR2C (0.33) | USP30PDE5AHTR2CADRA1AALOX5AP | |
| SCHEMBL13389438 | 0.82 | ALOX5AP (0.33) | USP30PDE5AHTR2CADRA1AALOX5AP | |
| SCHEMBL11894578 | 0.82 | KDM1A (0.32) | JAK2JAK1TYK2JAK3HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8398887-B2 | Liquid crystal compounds of butylenes | YANTAI VALIANT FINE CHEMICALS CO., LTD. (CN) | 2013-03-19 | — | — | US | disclosed |
| US-20110260106-A1 | LIQUID CRYSTAL COMPOUNDS OF BUTYLENES | VALIANT CORPORATION LIMITED (CN) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110260106-A1 | LIQUID CRYSTAL COMPOUNDS OF BUTYLENES | OR10J3, CNOT1, MYB | USP30 3563/4885PDE5A 4364/4885HTR2C 1582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.