Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT1 | P04628 | 3/20 | 0.58 |
| ▸ | GSK3B | P49841 | 3/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.58 |
| ▸ | ASIC3 | Q9UHC3 | 6/20 | 0.57 |
| ▸ | CLK2 | P49760 | 1/20 | 0.53 |
| ▸ | CLK3 | P49761 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 3/20 | 0.47 |
| ▸ | AXL | P30530 | 5/20 | 0.46 |
| ▸ | TYRO3 | Q06418 | 5/20 | 0.46 |
| ▸ | MERTK | Q12866 | 5/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | BPTF | Q12830 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26553745 | 0.94 | WNT1 (0.58) | WNT1GSK3BDYRK1AASIC3CLK2 | |
| SCHEMBL30480850 | 0.94 | WNT1 (0.58) | WNT1GSK3BDYRK1AASIC3CLK2 | |
| SCHEMBL19663486 | 0.80 | KDM1A (0.59) | WNT1GSK3BDYRK1AKDM1A | |
| SCHEMBL23199303 | 0.80 | KDM1A (0.59) | WNT1GSK3BDYRK1AKDM1A | |
| SCHEMBL31659654 | 0.78 | MAP4K1 (0.42) | WNT1GSK3BDYRK1AASIC3CLK2 | |
| SCHEMBL17785716 | 0.78 | KDM1A (0.48) | WNT1GSK3BDYRK1ACLK2CLK3 | |
| SCHEMBL21255300 | 0.78 | AXL (0.46) | KDM1AAXL | |
| SCHEMBL25404478 | 0.78 | ASIC3 (0.58) | WNT1GSK3BDYRK1AASIC3CD274 | |
| Hydrochloric Acid SCHEMBL25310878 | 0.77 | MAP4K1 (0.42) | WNT1GSK3BDYRK1AASIC3CLK2 | |
| Hydrochloric Acid SCHEMBL31184480 | 0.77 | MAP4K1 (0.42) | WNT1GSK3BDYRK1AASIC3CLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118742543-A | Dihydro isoquinoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-10-01 | — | — | CN | disclosed |
| WO-2023174383-A1 | DIHYDROISOQUINOLINE COMPOUND AND MEDICAL USE THEREOF | 中国科学院上海药物研究所 | 2023-09-21 | — | — | WO | disclosed |