Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | BACE1 | P56817 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25404886 | 1.00 | TP53 (0.54) | TP53ACHEBACE1BCHEALDH1A1 | |
| Hydrochloric Acid SCHEMBL25402582 | 0.98 | TP53 (0.53) | TP53ACHEBACE1BCHEALDH1A1 | |
| SCHEMBL14398343 | 0.90 | ALDH1A1 (0.56) | ACHEBACE1ALDH1A1LMNAPOLB | |
| SCHEMBL4847846 | 0.85 | ALDH1A1 (0.56) | TP53ACHEBACE1BCHEALDH1A1 | |
| SCHEMBL22254431 | 0.85 | ALDH1A1 (0.54) | TP53ACHEBACE1BCHEALDH1A1 | |
| SCHEMBL16122102 | 0.84 | CYP2D6 (0.57) | TP53ACHEBACE1BCHEALDH1A1 | |
| SCHEMBL242758 | 0.83 | CCR3 (0.62) | ACHEBACE1BCHEALDH1A1CXCR4 | |
| SCHEMBL1180490 | 0.83 | CCR3 (0.62) | ACHEBACE1BCHEALDH1A1CXCR4 | |
| SCHEMBL3074896 | 0.83 | CCR3 (0.62) | ACHEBACE1BCHEALDH1A1CXCR4 | |
| SCHEMBL3172847 | 0.81 | CYP2D6 (0.62) | ALDH1A1POLBCXCR4KCNH2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4463452-A2 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | Anima Biotech Inc. (US) | 2024-11-20 | — | — | EP | disclosed |
| WO-2023177700-A2 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2023-09-21 | — | — | WO | disclosed |