Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4854395 | 0.90 | GAA (0.59) | ALDH1A1TP53GAAMEN1KMT2A | |
| SCHEMBL4848099 | 0.90 | ALDH1A1 (0.64) | ALDH1A1CXCR4MEN1KMT2ABCHE | |
| Hydrochloric Acid SCHEMBL29525233 | 0.88 | ALDH1A1 (0.62) | ALDH1A1CXCR4MEN1KMT2ABCHE | |
| SCHEMBL25404886 | 0.85 | TP53 (0.54) | ALDH1A1TP53CXCR4MEN1KMT2A | |
| SCHEMBL25403170 | 0.85 | TP53 (0.54) | ALDH1A1TP53CXCR4MEN1KMT2A | |
| SCHEMBL3074896 | 0.85 | CCR3 (0.62) | ALDH1A1GAACXCR4BCHEACHE | |
| SCHEMBL1180490 | 0.85 | CCR3 (0.62) | ALDH1A1GAACXCR4BCHEACHE | |
| SCHEMBL242758 | 0.85 | CCR3 (0.62) | ALDH1A1GAACXCR4BCHEACHE | |
| SCHEMBL7827240 | 0.84 | SMN1; SMN2 (0.54) | ALDH1A1CXCR4MEN1KMT2AKDM4E | |
| SCHEMBL7826768 | 0.84 | SMN1; SMN2 (0.54) | ALDH1A1CXCR4MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7390830-B1 | Remedies or prophylactics for diseases in association with chemokines | TEIJIN LIMITED (JP) | 2008-06-24 | — | — | US | disclosed |
| EP-1179341-B1 | REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES | TEIJIN LTD (JP) | 2005-11-09 | — | — | EP | disclosed |
| EP-1553085-A1 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-07-13 | — | — | EP | disclosed |
| EP-1535909-A2 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-06-01 | — | — | EP | disclosed |
| CN-1384743-A | Remedies or preventives for diseases in association with chemokines | TEIJIN LTD (JP) | 2002-12-11 | — | — | CN | disclosed |
| US-6451842-B1 | Cyclic amine derivatives and their use as drugs | DUPONT PHARMACEUTICALS COMPANY | 2002-09-17 | — | — | US | disclosed |
| US-6410566-B1 | ATHEROSCLEROSIS; ANTIARTHRITIC AGENTS | TEIJIN LIMITED (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6362177-B1 | INHIBITION OF CHEMOKINE BINDING | TEIJIN LIMITED (JP) | 2002-03-26 | — | — | US | disclosed |
| EP-1179341-A1 | REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES | TEIJIN LIMITED (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-1030840-A1 | CYCLIC AMINE DERIVATIVES AND THEIR USE AS DRUGS | TEIJIN LIMITED (JP) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999025686-A1 | CYCLIC AMINE DERIVATIVES AND THEIR USE AS DRUGS | TEIJIN LIMITED (JP) | 1999-05-27 | — | — | WO | disclosed |