Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30987858 | 0.81 | CA1 (0.44) | TDP1CA1CA2CA5ACA9 | |
| SCHEMBL22501317 | 0.75 | PTGS2 (0.50) | PTGS1LMNABLMCA1CA2 | |
| SCHEMBL28331462 | 0.74 | CA1 (0.41) | LMNABLMCA1CA2CA5A | |
| SCHEMBL15248159 | 0.74 | CYP51A1 (0.42) | TDP1CA1CA2CA5ACA9 | |
| SCHEMBL15239822 | 0.74 | CYP51A1 (0.42) | TDP1CA1CA2CA5ACA9 | |
| SCHEMBL1648986 | 0.73 | TDP1 (0.65) | NR1I2PTGS1ADRA1ALMNABLM | |
| SCHEMBL21853744 | 0.73 | TDP1 (0.65) | NR1I2PTGS1ADRA1ALMNABLM | |
| SCHEMBL3502211 | 0.73 | TDP1 (0.65) | NR1I2PTGS1ADRA1ALMNABLM | |
| SCHEMBL26912718 | 0.73 | TDP1 (0.65) | NR1I2PTGS1ADRA1ALMNABLM | |
| SCHEMBL4728748 | 0.73 | LMNA (0.58) | NR1I2PTGS1ADRA1ALMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178318-A2 | L-THREONINE TRANSALDOLASES AND USES THEREOF | KUNJAPUR ADITYA (US) | 2023-09-21 | — | — | WO | disclosed |