Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 5/20 | 0.46 |
| ▸ | PLAAT3 | P53816 | 3/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 3/20 | 0.45 |
| ▸ | PLAAT2 | Q9NWW9 | 3/20 | 0.45 |
| ▸ | PLAAT4 | Q9UL19 | 3/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23588129 | 0.89 | HDAC1 (0.57) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL16697880 | 0.82 | TAAR1 (0.45) | HDAC1HDAC6HDAC2HDAC8IDO1 | |
| SCHEMBL25801556 | 0.80 | POLB (0.46) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL23578342 | 0.80 | TAAR1 (0.43) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL641405 | 0.79 | IDO1 (0.44) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL1342679 | 0.79 | HDAC2 (0.59) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL4847288 | 0.75 | IDO1 (0.58) | IDO1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL26784352 | 0.75 | IDO1 (0.48) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| Hydrochloric Acid SCHEMBL4715995 | 0.73 | IDO1 (0.56) | IDO1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL27865593 | 0.72 | PLAAT3 (0.49) | HDAC1HDAC6HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044069-B2 | Compounds as calcium channel blockers | ABBOTT LABORATORIES (US) | 2011-10-25 | — | — | US | disclosed |
| US-20100093730-A1 | NOVEL COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | ABBOTT LABORATORIES (US) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093730-A1 | NOVEL COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | CACNA1E, CACNA1S, CACNA1D | HDAC1 1048/4885HDAC6 2606/4885HDAC3 1606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.