SCHEMBL25801556

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23578342	0.88	TAAR1 (0.43)	LPLLIPGHDAC1HDAC2HDAC8
	SCHEMBL23578295	0.84	POLB (0.46)	POLBCTDSP1LPLLIPGHDAC6
	SCHEMBL16697880	0.82	TAAR1 (0.45)	POLBCTDSP1HDAC1HDAC2HDAC8
	SCHEMBL2540337	0.80	HDAC1 (0.51)	POLBCTDSP1HDAC1HDAC2HDAC8
	SCHEMBL1342679	0.79	HDAC2 (0.59)	HDAC1HDAC2HDAC8HDAC6HDAC3
	SCHEMBL14472965	0.76	PLK1 (0.52)	POLBCTDSP1LPLLIPGHDAC1
	SCHEMBL24802224	0.73	ALDH1A1 (0.55)	POLBHDAC6HDAC10PLK1KDM4E
	SCHEMBL142480	0.72	LPL (0.62)	POLBCTDSP1LPLLIPGPLK1
	SCHEMBL25801814	0.72	ALDH1A1 (0.56)	LPLLIPGKDM4EALDH1A1
	Hydroxyamine SCHEMBL17181093	0.70	LPL (0.61)	LPLLIPGPLK1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.