Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.78 |
| ▸ | CYP19A1 | P11511 | 10/20 | 0.78 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.68 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | PLD2 | O14939 | 1/20 | 0.65 |
| ▸ | ESRRB | O95718 | 1/20 | 0.65 |
| ▸ | PGR | P06401 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3809258 | 0.94 | ESR1 (0.75) | ESR1CYP19A1ESR2CYP3A4PTGS2 | |
| SCHEMBL10777096 | 0.94 | ESR1 (0.75) | ESR1CYP19A1ESR2CYP3A4PTGS2 | |
| SCHEMBL10780099 | 0.94 | PTGS2 (0.76) | ESR1CYP19A1ESR2CYP3A4PTGS2 | |
| SCHEMBL10777091 | 0.94 | ESR1 (0.75) | ESR1CYP19A1ESR2CYP3A4PTGS2 | |
| SCHEMBL12134458 | 0.91 | CYP19A1 (0.67) | ESR1CYP19A1ESR2CYP3A4PTGS2 | |
| SCHEMBL639225 | 0.88 | ESR1 (1.00) | ESR1CYP19A1ESR2CYP3A4PTGS2 | |
| SCHEMBL7723356 | 0.88 | ESR1 (1.00) | ESR1CYP19A1ESR2CYP3A4PTGS2 | |
| SCHEMBL5354173 | 0.88 | ESR1 (1.00) | ESR1CYP19A1ESR2CYP3A4PTGS2 | |
| SCHEMBL5818558 | 0.88 | ESR1 (1.00) | ESR1CYP19A1ESR2CYP3A4PTGS2 | |
| SCHEMBL23851086 | 0.88 | ESR1 (1.00) | ESR1CYP19A1ESR2CYP3A4PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066286-A1 | COMPOSITIONS OF (Z)-ENDOXIFEN AND METHODS OF ENRICHMENT THEREOF | ATOSSA THERAPEUTICS, INC. | 2025-02-27 | — | — | US | claimed |
| EP-4463437-A2 | COMPOSITIONS OF (Z)-ENDOXIFEN AND METHODS OF ENRICHMENT THEREOF | Atossa Therapeutics, Inc. (US) | 2024-11-20 | — | — | EP | claimed |
| CN-118647598-A | Compositions of (Z) -idoxifene and methods of enriching same | 阿托萨治疗学公司 | 2024-09-13 | — | — | CN | claimed |
| WO-2023137044-A2 | COMPOSITIONS OF (Z)-ENDOXIFEN AND METHODS OF ENRICHMENT THEREOF | ATOSSA THERAPEUTICS, INC. (US) | 2023-07-20 | — | — | WO | claimed |
| US-20250066286-A1 | COMPOSITIONS OF (Z)-ENDOXIFEN AND METHODS OF ENRICHMENT THEREOF | ATOSSA THERAPEUTICS, INC. | 2025-02-27 | — | — | US | disclosed |
| EP-4463437-A2 | COMPOSITIONS OF (Z)-ENDOXIFEN AND METHODS OF ENRICHMENT THEREOF | Atossa Therapeutics, Inc. (US) | 2024-11-20 | — | — | EP | disclosed |
| CN-118647598-A | Compositions of (Z) -idoxifene and methods of enriching same | 阿托萨治疗学公司 | 2024-09-13 | — | — | CN | disclosed |
| WO-2023137044-A2 | COMPOSITIONS OF (Z)-ENDOXIFEN AND METHODS OF ENRICHMENT THEREOF | ATOSSA THERAPEUTICS, INC. (US) | 2023-07-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066286-A1 | COMPOSITIONS OF (Z)-ENDOXIFEN AND METHODS OF ENRICHMENT THEREOF | ZYX, LITAF, CYP4F2 | ESR1 805/4885CYP19A1 427/4885ESR2 403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.