Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 8/20 | 0.50 |
| ▸ | F10 | P00742 | 3/20 | 0.47 |
| ▸ | CPB1 | P15086 | 11/20 | 0.47 |
| ▸ | CPA1 | P15085 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2536622 | 1.00 | CPB2 (0.50) | CPB2F10CPB1CPA1 | |
| SCHEMBL2538781 | 0.93 | CPB2 (0.51) | CPB2F10CPB1CPA1 | |
| SCHEMBL2536812 | 0.90 | CPB2 (0.64) | CPB2F10CPB1CPA1 | |
| SCHEMBL2540873 | 0.90 | CPB2 (0.64) | CPB2F10CPB1CPA1 | |
| SCHEMBL2537259 | 0.90 | CPB2 (0.64) | CPB2F10CPB1CPA1 | |
| Trifluoroacetic Acid SCHEMBL2543615 | 0.88 | CPB1 (0.51) | CPB2F10CPB1CPA1 | |
| SCHEMBL2535386 | 0.82 | CPB1 (0.57) | CPB2CPB1CPA1 | |
| SCHEMBL2542697 | 0.81 | CPB2 (0.58) | CPB2CPB1CPA1 | |
| SCHEMBL2536330 | 0.79 | CPB2 (0.64) | CPB2CPB1CPA1 | |
| SCHEMBL2536326 | 0.78 | CPB2 (0.71) | CPB2CPB1CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937673-B1 | IMIDAZOLE DERIVATIVES AS INHIBITORS OF TAFIA | SANOFI SA (FR) | 2015-10-21 | — | — | EP | claimed |
| US-8044208-B2 | inhibit the enzyme TAFIa (activated thrombin-activatable fibrinolysis inhibitor); 3-(6-aminopyridin-3-yl)-2-{1-[5-(5-chlorothiophen-2-yl)isoxazol-3-ylmethyl]-1H-imidazol-4-yl}propionic acid | SANOFI-AVENTIS (FR) | 2011-10-25 | — | — | US | claimed |
| EP-1937673-B1 | IMIDAZOLE DERIVATIVES AS INHIBITORS OF TAFIA | SANOFI SA (FR) | 2015-10-21 | — | — | EP | disclosed |
| US-8044208-B2 | inhibit the enzyme TAFIa (activated thrombin-activatable fibrinolysis inhibitor); 3-(6-aminopyridin-3-yl)-2-{1-[5-(5-chlorothiophen-2-yl)isoxazol-3-ylmethyl]-1H-imidazol-4-yl}propionic acid | SANOFI-AVENTIS (FR) | 2011-10-25 | — | — | US | disclosed |