SCHEMBL25404657

SCHEMBL25404657

Oc1c(Cc2ccccc2)cccc1-c1ccc2ccccc2c1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.54
HDAC2 Q92769 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
ELANE P08246 2/20 0.46
CTSG P08311 1/20 0.45
CYP11B1 P15538 1/20 0.44
CYP11B2 P19099 1/20 0.44
HSD17B1 P14061 1/20 0.44
HSD17B2 P37059 1/20 0.44
BCL2 P10415 1/20 0.43
BCL2L1 Q07817 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25404841 0.91 HDAC4 (0.54) HDAC4HDAC2HDAC8HSD17B1HSD17B2
SCHEMBL25405478 0.85 ALOX5 (0.51) HDAC4HDAC2HDAC8CYP11B1CYP11B2
SCHEMBL31144999 0.84 HDAC4 (0.53) HDAC4HDAC2HDAC8CYP2C9CYP2C19
SCHEMBL29738651 0.82 ELANE (0.54) HDAC4HDAC2HDAC8ELANECTSG
SCHEMBL8607293 0.82 ELANE (0.54) HDAC4HDAC2HDAC8ELANECTSG
SCHEMBL598168 0.80 HDAC4 (0.72) HDAC4HDAC2HDAC8CYP1A2CYP2D6
SCHEMBL30335758 0.80 HDAC4 (0.72) HDAC4HDAC2HDAC8CYP1A2CYP2D6
SCHEMBL28061095 0.79 HDAC4 (0.66) HDAC4HDAC2HDAC8CYP1A2CYP2D6
SCHEMBL28560168 0.78 GSTP1 (0.45) HDAC4HDAC2HDAC8CYP1A2CYP2D6
SCHEMBL25403651 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4617737-A2 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-09-17 EP disclosed
US-20250223400-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-07-10 US disclosed
EP-4506392-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-02-12 EP disclosed
WO-2023195504-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME 三菱瓦斯化学株式会社 2023-10-12 WO disclosed
WO-2023176736-A1 NOVEL 1,3-BIS(1-METHYL-1-PHENYLETHYL)BENZENE COMPOUND 本州化学工業株式会社 2023-09-21 WO disclosed