SCHEMBL25404841

SCHEMBL25404841

Oc1c(Cc2ccc3ccccc3c2)cccc1-c1ccc2ccccc2c1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.54
HDAC2 Q92769 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
ALOX5 P09917 2/20 0.51
TBXA2R P21731 1/20 0.45
PTGER4 P35408 1/20 0.45
PTGFR P43088 1/20 0.45
PTGER3 P43115 1/20 0.45
PTGER2 P43116 1/20 0.45
PTGDR Q13258 1/20 0.45
HSD17B1 P14061 1/20 0.44
HSD17B2 P37059 1/20 0.44
ESR2 Q92731 2/20 0.42
GSTP1 P09211 1/20 0.42
ESR1 P03372 1/20 0.42
CETP P11597 1/20 0.42
SOX18 P35713 1/20 0.42
AKR1B1 P15121 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25405478 0.91 ALOX5 (0.51) HDAC4HDAC2HDAC8ALOX5TBXA2R
SCHEMBL25404657 0.91 HDAC4 (0.54) HDAC4HDAC2HDAC8HSD17B1HSD17B2
SCHEMBL31144999 0.84 HDAC4 (0.53) HDAC4HDAC2HDAC8HSD17B1HSD17B2
SCHEMBL25403897 0.84 ALOX5 (0.50) ALOX5
SCHEMBL598168 0.80 HDAC4 (0.72) HDAC4HDAC2HDAC8ALOX5HSD17B1
SCHEMBL30335758 0.80 HDAC4 (0.72) HDAC4HDAC2HDAC8ALOX5HSD17B1
SCHEMBL26576840 0.75 TBXA2R (0.40) ALOX5TBXA2RPTGER4PTGFRPTGER3
SCHEMBL19211556 0.75 HDAC4 (0.66) HDAC4HDAC2HDAC8ALOX5HSD17B1
SCHEMBL28061095 0.75 HDAC4 (0.66) HDAC4HDAC2HDAC8ALOX5HSD17B1
SCHEMBL1527812 0.75 ALOX5 (0.72) ALOX5TBXA2RPTGER4PTGFRPTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4617737-A2 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-09-17 EP disclosed
US-20250223400-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-07-10 US disclosed
EP-4506392-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-02-12 EP disclosed
CN-118786109-A Novel 1, 3-bis (1-methyl-1-phenylethyl) benzene compound 本州化学工业株式会社 2024-10-15 CN disclosed
WO-2023195504-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME 三菱瓦斯化学株式会社 2023-10-12 WO disclosed
WO-2023176736-A1 NOVEL 1,3-BIS(1-METHYL-1-PHENYLETHYL)BENZENE COMPOUND 本州化学工業株式会社 2023-09-21 WO disclosed