Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.39 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1009505 | 0.78 | ALDH1A1 (0.48) | ALDH1A1LMNAPOLBRXRARXRB | |
| SCHEMBL5918317 | 0.78 | ALDH1A1 (0.48) | ALDH1A1LMNAPOLBRXRARXRB | |
| SCHEMBL15889590 | 0.78 | ALDH1A1 (0.48) | ALDH1A1LMNAPOLBRXRARXRB | |
| SCHEMBL158414 | 0.78 | CYP4F2 (0.52) | ALDH1A1LMNAPOLBRXRARXRB | |
| SCHEMBL766981 | 0.76 | RXRA (0.55) | ALDH1A1LMNAPOLBRXRARXRB | |
| SCHEMBL21470492 | 0.75 | KDM5B (0.38) | ALDH1A1LMNAPOLBRXRARXRB | |
| SCHEMBL8740164 | 0.75 | ALDH1A1 (0.45) | ALDH1A1LMNAPOLBRXRARXRB | |
| SCHEMBL22499381 | 0.73 | RXRA (0.44) | ALDH1A1LMNAPOLBRXRARXRB | |
| SCHEMBL13026225 | 0.72 | RXRA (0.46) | ALDH1A1LMNAPOLBRXRARXRB | |
| SCHEMBL31104397 | 0.71 | RXRA (0.45) | ALDH1A1LMNAPOLBRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134629-A1 | NUCLEAR TRANSPORT REGULATOR AND USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-20 | — | — | WO | disclosed |
| WO-2023134629-A1 | NUCLEAR TRANSPORT REGULATOR AND USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-20 | — | — | WO | disclosed |