SCHEMBL25405347

SCHEMBL25405347

CC(C)(C)OC(=O)c1ccn(C(=O)N2CCC3(CCCN3Cc3ccc(C(F)(F)F)cc3N3CCCC3)CC2)n1

nearest known ligand 0.81

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FAAH O00519 6/20 0.81
MGLL Q99685 10/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30372000 1.00 FAAH (0.81) FAAHMGLL
SCHEMBL30371754 0.90 FAAH (1.00) FAAHMGLL
SCHEMBL20567221 0.90 FAAH (1.00) FAAHMGLL
Acetone SCHEMBL25405187 0.89 FAAH (0.95) FAAHMGLL
SCHEMBL20566783 0.89 FAAH (0.98) FAAHMGLL
SCHEMBL20567015 0.89 FAAH (0.86) FAAHMGLL
Hydrochloric Acid SCHEMBL30371914 0.89 FAAH (0.98) FAAHMGLL
Hydrochloric Acid SCHEMBL25406454 0.89 FAAH (0.98) FAAHMGLL
SCHEMBL30420225 0.89 FAAH (0.86) FAAHMGLL
SCHEMBL30420822 0.89 FAAH (0.98) FAAHMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4426696-B1 CRYSTALLINE FORMS OF A MONOACYLGLYCEROL LIPASE INHIBITOR H LUNDBECK AS (DK) 2026-05-06 EP disclosed
US-12152029-B2 Crystalline forms of a MAGL inhibitor H. LUNDBECK A/S (DK) 2024-11-26 US disclosed
US-20230265095-A1 CRYSTALLINE FORMS OF A MAGL INHIBITOR LUNDBECK LA JOLLA RESEARCH CENTER, INC. 2023-08-24 US disclosed
US-20230265095-A1 CRYSTALLINE FORMS OF A MAGL INHIBITOR LUNDBECK LA JOLLA RESEARCH CENTER, INC. 2023-08-24 US disclosed
US-20230265095-A1 CRYSTALLINE FORMS OF A MAGL INHIBITOR LUNDBECK LA JOLLA RESEARCH CENTER, INC. 2023-08-24 US disclosed
WO-2023078868-A1 CRYSTALLINE FORMS OF A MONOACYLGLYCEROL LIPASE INHIBITOR H. LUNDBECK A/S (DK) 2023-05-11 WO disclosed
WO-2023078868-A1 CRYSTALLINE FORMS OF A MONOACYLGLYCEROL LIPASE INHIBITOR H. LUNDBECK A/S (DK) 2023-05-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12152029-B2 Crystalline forms of a MAGL inhibitor MAG, MAGI3, PYM1 FAAH 457/4885MGLL 7/4885
US-20230265095-A1 CRYSTALLINE FORMS OF A MAGL INHIBITOR MAG, PYM1, MAGI3 FAAH 252/4885MGLL 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.