SCHEMBL20567221

SCHEMBL20567221

O=C(O)c1ccn(C(=O)N2CCC3(CCCN3Cc3ccc(C(F)(F)F)cc3N3CCCC3)CC2)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FAAH O00519 8/20 1.00
MGLL Q99685 11/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30371754 1.00 FAAH (1.00) FAAHMGLL
Hydrochloric Acid SCHEMBL25406454 0.99 FAAH (0.98) FAAHMGLL
SCHEMBL20566783 0.99 FAAH (0.98) FAAHMGLL
Hydrochloric Acid SCHEMBL30371914 0.99 FAAH (0.98) FAAHMGLL
SCHEMBL30420822 0.99 FAAH (0.98) FAAHMGLL
Acetone SCHEMBL25405187 0.98 FAAH (0.95) FAAHMGLL
Dioxane SCHEMBL25406534 0.96 FAAH (0.92) FAAHMGLL
SCHEMBL20566532 0.94 FAAH (0.88) FAAHMGLL
SCHEMBL20566597 0.94 FAAH (0.88) FAAHMGLL
SCHEMBL30218747 0.94 FAAH (0.88) FAAHMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4426696-B1 CRYSTALLINE FORMS OF A MONOACYLGLYCEROL LIPASE INHIBITOR H LUNDBECK AS (DK) 2026-05-06 EP claimed
US-12152029-B2 Crystalline forms of a MAGL inhibitor H. LUNDBECK A/S (DK) 2024-11-26 US claimed
US-20230265095-A1 CRYSTALLINE FORMS OF A MAGL INHIBITOR LUNDBECK LA JOLLA RESEARCH CENTER, INC. 2023-08-24 US claimed
WO-2023078868-A1 CRYSTALLINE FORMS OF A MONOACYLGLYCEROL LIPASE INHIBITOR H. LUNDBECK A/S (DK) 2023-05-11 WO claimed
EP-4426696-B1 CRYSTALLINE FORMS OF A MONOACYLGLYCEROL LIPASE INHIBITOR H LUNDBECK AS (DK) 2026-05-06 EP disclosed
US-12152029-B2 Crystalline forms of a MAGL inhibitor H. LUNDBECK A/S (DK) 2024-11-26 US disclosed
US-12152029-B2 Crystalline forms of a MAGL inhibitor H. LUNDBECK A/S (DK) 2024-11-26 US disclosed
EP-4426696-A1 CRYSTALLINE FORMS OF A MONOACYLGLYCEROL LIPASE INHIBITOR H. Lundbeck A/S (DK) 2024-09-11 EP disclosed
US-20230265095-A1 CRYSTALLINE FORMS OF A MAGL INHIBITOR LUNDBECK LA JOLLA RESEARCH CENTER, INC. 2023-08-24 US disclosed
US-20230265095-A1 CRYSTALLINE FORMS OF A MAGL INHIBITOR LUNDBECK LA JOLLA RESEARCH CENTER, INC. 2023-08-24 US disclosed
US-20230265095-A1 CRYSTALLINE FORMS OF A MAGL INHIBITOR LUNDBECK LA JOLLA RESEARCH CENTER, INC. 2023-08-24 US disclosed
US-20230265095-A1 CRYSTALLINE FORMS OF A MAGL INHIBITOR LUNDBECK LA JOLLA RESEARCH CENTER, INC. 2023-08-24 US disclosed
US-20210053960-A1 PYRAZOLE MAGL INHIBITORS H. LUNDBECK A/S (DK) 2021-02-25 US disclosed
US-20210053960-A1 PYRAZOLE MAGL INHIBITORS H. LUNDBECK A/S (DK) 2021-02-25 US disclosed
US-10927105-B1 Pyrazole MAGL inhibitors LUNDBECK LA JOLLA RESEARCH CENTER, INC. (US) 2021-02-23 US disclosed
US-10927105-B1 Pyrazole MAGL inhibitors LUNDBECK LA JOLLA RESEARCH CENTER, INC. (US) 2021-02-23 US disclosed
WO-2020112905-A1 METHODS OF TREATING DISEASE WITH MAGL INHIBITORS LUNDBECK LA JOLLA RESEARCH CENTER, INC. (US) 2020-06-04 WO disclosed
US-10266497-B2 Pyrazole MAGL inhibitors ABIDE THERAPEUTICS, INC. (US) 2019-04-23 US disclosed
US-10266497-B2 Pyrazole MAGL inhibitors ABIDE THERAPEUTICS, INC. (US) 2019-04-23 US disclosed
US-20180339970-A1 PYRAZOLE MAGL INHIBITORS H. LUNDBECK A/S (DK) 2018-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180339970-A1 PYRAZOLE MAGL INHIBITORS MGLL, PNLIP, LPL FAAH 33/4885MGLL 1/4885
US-12152029-B2 Crystalline forms of a MAGL inhibitor MAG, MAGI3, PYM1 FAAH 457/4885MGLL 7/4885
US-10266497-B2 Pyrazole MAGL inhibitors MGLL, PNLIP, LPL FAAH 33/4885MGLL 1/4885
US-20210053960-A1 PYRAZOLE MAGL INHIBITORS MGLL, PNLIP, LPL FAAH 33/4885MGLL 1/4885
US-20230265095-A1 CRYSTALLINE FORMS OF A MAGL INHIBITOR MAG, PYM1, MAGI3 FAAH 252/4885MGLL 7/4885
US-10927105-B1 Pyrazole MAGL inhibitors MGLL, PNLIP, LPL FAAH 33/4885MGLL 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.