SCHEMBL951795

SCHEMBL951795

CN(C)CCCCCCCCCCCC=O

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.58
ALDH1A1 P00352 1/20 0.58
DNM1 Q05193 3/20 0.48
FAAH O00519 2/20 0.46
TRPV1 Q8NER1 2/20 0.46
HIF1A Q16665 1/20 0.45
KDM4A O75164 3/20 0.39
KDM4C Q9H3R0 3/20 0.39
KDM4E B2RXH2 1/20 0.37
PAOX Q6QHF9 1/20 0.36
SIGMAR1 Q99720 2/20 0.35
KDM5A P29375 1/20 0.35
KDM7A Q6ZMT4 1/20 0.35
PHF8 Q9UPP1 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL334434 1.00 TSHR (0.58) TSHRALDH1A1DNM1FAAHTRPV1
SCHEMBL7282265 1.00 TSHR (0.58) TSHRALDH1A1DNM1FAAHTRPV1
SCHEMBL7294715 1.00 TSHR (0.58) TSHRALDH1A1DNM1FAAHTRPV1
SCHEMBL7284860 1.00 TSHR (0.58) TSHRALDH1A1DNM1FAAHTRPV1
SCHEMBL7291004 1.00 TSHR (0.58) TSHRALDH1A1DNM1FAAHTRPV1
SCHEMBL18807792 1.00 TSHR (0.58) TSHRALDH1A1DNM1FAAHTRPV1
SCHEMBL7285272 1.00 TSHR (0.58) TSHRALDH1A1DNM1FAAHTRPV1
Iodide SCHEMBL25402951 0.97 TSHR (0.55) TSHRALDH1A1DNM1FAAHTRPV1
SCHEMBL5226044 0.97 TSHR (0.55) TSHRALDH1A1DNM1FAAHTRPV1
Bromide SCHEMBL25406243 0.97 TSHR (0.55) TSHRALDH1A1DNM1FAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9801850-B2 Antibacterial agent OSAKA UNIVERSITY (JP) 2017-10-31 US claimed
US-20150111961-A1 MEMBRANE FUSION INHIBITOR PROTECTEA, LTD. (JP) 2015-04-23 US claimed
EP-2460405-A1 ANTIBACTERIAL AGENT Osaka University (JP) 2012-06-06 EP claimed
US-20120136049-A1 ANTIBACTERIAL AGENT OSAKA UNIVERSITY (JP) 2012-05-31 US claimed
CN-102480952-A Antibacterial agent UNIV OSAKA 2012-05-30 CN claimed
US-20110003889-A1 MEMBRANE FUSION INHIBITOR KAIHATSU, Kunihiro (JP) 2011-01-06 US claimed
CN-101932320-A Membrane fusion inhibitor KUNIHIRO KAIHATSU 2010-12-29 CN claimed
US-9901565-B2 Membrane fusion inhibitor PROTECTEA, LTD. (JP) 2018-02-27 US disclosed
US-9801850-B2 Antibacterial agent OSAKA UNIVERSITY (JP) 2017-10-31 US disclosed
US-20150111961-A1 MEMBRANE FUSION INHIBITOR PROTECTEA, LTD. (JP) 2015-04-23 US disclosed
EP-2460405-B1 EPIGALLOCATECHIN GALLATE DERIVATIVE AS ANTIBACTERIAL AGENT UNIV OSAKA (JP) 2015-03-18 EP disclosed
US-8952055-B2 Membrane fusion inhibitor PROTECTEA, LTD. (JP) 2015-02-10 US disclosed
CN-102480952-B Antibacterial agent UNIV OSAKA NAT UNIV CORP 2015-01-21 CN disclosed
CN-101932320-B Membrane fusion inhibitor KAIHATSU KUNIHIRO 2014-06-18 CN disclosed
EP-2460405-A1 ANTIBACTERIAL AGENT Osaka University (JP) 2012-06-06 EP disclosed
US-20120136049-A1 ANTIBACTERIAL AGENT OSAKA UNIVERSITY (JP) 2012-05-31 US disclosed
CN-102480952-A Antibacterial agent UNIV OSAKA 2012-05-30 CN disclosed
US-20110003889-A1 MEMBRANE FUSION INHIBITOR KAIHATSU, Kunihiro (JP) 2011-01-06 US disclosed
CN-101932320-A Membrane fusion inhibitor KUNIHIRO KAIHATSU 2010-12-29 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136049-A1 ANTIBACTERIAL AGENT TEAD4, ELOVL6, TEAD1 TSHR 2877/4885ALDH1A1 677/4885DNM1 812/4885
US-20150111961-A1 MEMBRANE FUSION INHIBITOR FLOT1, NSF, VAMP7 TSHR 2134/4885ALDH1A1 2332/4885DNM1 20/4885
US-20110003889-A1 MEMBRANE FUSION INHIBITOR FLOT1, NSF, VAMP7 TSHR 2134/4885ALDH1A1 2332/4885DNM1 20/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.