Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 4/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24630651 | 0.77 | GPR17 (0.42) | DAOGPR17JAK2GSK3BKDM4E | |
| SCHEMBL29939832 | 0.71 | DAO (0.59) | DAOMETAP2CHEK1AURKADAPK3 | |
| SCHEMBL16921428 | 0.71 | DAO (0.59) | DAOMETAP2CHEK1AURKADAPK3 | |
| SCHEMBL12069883 | 0.68 | CASP6 (0.54) | DAOCASP6MEN1ALDH1A1MAPT | |
| SCHEMBL25375632 | 0.67 | GPR17 (0.38) | DAOGPR17MEN1MAPTKMT2A | |
| SCHEMBL25318777 | 0.67 | HSD17B10 (0.42) | GPR17KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL25986570 | 0.67 | GPR17 (0.38) | GPR17KDM4EALDH1A1 | |
| SCHEMBL31302839 | 0.67 | HSD17B10 (0.42) | GPR17KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL21617924 | 0.67 | KDM1A (0.38) | GPR17KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL18149616 | 0.67 | ALOX5 (0.41) | GPR17ALOX5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138612-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS HPK1 INHIBITORS | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-27 | — | — | WO | disclosed |