Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL853115 | 0.82 | GRM5 (0.38) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL25409979 | 0.81 | KMT2A (0.41) | MAPTMEN1KMT2ALMNANPC1 | |
| SCHEMBL6553332 | 0.73 | FFAR1 (0.41) | MEN1KMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL6553345 | 0.72 | CYP3A4 (0.46) | MEN1KMT2ACYP3A4NPC1KDM4E | |
| SCHEMBL20893408 | 0.72 | ALDH1A1 (0.44) | MEN1KMT2ALMNACYP1A2NPC1 | |
| SCHEMBL2433672 | 0.70 | APP (0.45) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL11236951 | 0.70 | LMNA (0.51) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL20066494 | 0.70 | FFAR1 (0.37) | MAPTMEN1KMT2ALMNACYP3A4 | |
| SCHEMBL18180534 | 0.69 | FFAR1 (0.36) | MAPTMEN1KMT2ALMNACYP3A4 | |
| SCHEMBL6828449 | 0.69 | GRM5 (0.53) | MAPTLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138675-A1 | QUINOLINE COMPOUND AND USE THEREOF | 默达药物（香港）有限公司 | 2023-07-27 | — | — | WO | disclosed |
| CN-116478129-A | Quinoline compound and use thereof | 深圳默元生物科技有限公司 | 2023-07-25 | — | — | CN | disclosed |