Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31366649 | 1.00 | VCAM1 (0.57) | VCAM1ALDH1A1MAPK1GAACYP19A1 | |
| Methylamine SCHEMBL27483022 | 0.96 | MAPK1 (0.54) | VCAM1ALDH1A1MAPK1GAACYP19A1 | |
| SCHEMBL10396627 | 0.90 | ALDH1A1 (0.58) | VCAM1ALDH1A1MAPK1GAATSHR | |
| SCHEMBL11289155 | 0.88 | HPGD (0.59) | VCAM1ALDH1A1MAPK1POLBBCL2L1 | |
| SCHEMBL27631145 | 0.85 | VCAM1 (0.49) | VCAM1ALDH1A1MAPK1GAAMITF | |
| SCHEMBL21202543 | 0.84 | ALDH1A1 (0.52) | VCAM1ALDH1A1MAPK1GAACYP19A1 | |
| SCHEMBL343417 | 0.84 | ALDH1A1 (0.52) | VCAM1ALDH1A1MAPK1GAATSHR | |
| SCHEMBL13240120 | 0.83 | RECQL (0.65) | VCAM1ALDH1A1MAPK1GAATSHR | |
| SCHEMBL28081755 | 0.83 | ALDH1A1 (0.57) | VCAM1ALDH1A1MAPK1GAACYP19A1 | |
| SCHEMBL11294315 | 0.82 | VCAM1 (0.55) | VCAM1ALDH1A1MAPK1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250197360-A1 | NOVEL DIAZEPINES THAT TARGET YELLOW FEVER VIRUS NON-STRUCTURAL 4B (NS4B) PROTEIN AND THEIR METHOD OF USE | BARUCH S. BLUMBERG INSTITUTE | 2025-06-19 | — | — | US | disclosed |
| WO-2023172726-A1 | NOVEL DIAZEPINES THAT TARGET YELLOW FEVER VIRUS NON-STRUCTURAL 4B (NS4B) PROTEIN AND THEIR METHOD OF USE | BARUCH S. BLUMBERG INSTITUTE (US) | 2023-09-14 | — | — | WO | disclosed |
| CN-106413710-A | Factor xia inhibitors | 默沙东公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-103717588-B | Pyrazole derivatives | 绿色科技株式会社 | 2016-08-03 | — | — | CN | disclosed |
| CN-101141880-A | Herbicidal compositions based on 3-phenyluracil and 3-sulfonylisoxazole 58743 | BASF AG (DE) | 2008-03-12 | — | — | CN | disclosed |
| CN-1191049-C | Cationic monophenyl-nitro-diamino compounds and use in dyeing cutin fiber, dyeing composition containing said matter | OREAL (FR) | 2005-03-02 | — | — | CN | disclosed |
| CN-1261529-A | Cationic monophenyl-nitro-diamino compounds and use in dyeing cutin fiber, dyeing composition containing said matter | OREAL (FR) | 2000-08-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250197360-A1 | NOVEL DIAZEPINES THAT TARGET YELLOW FEVER VIRUS NON-STRUCTURAL 4B (NS4B) PROTEIN AND THEIR METHOD OF USE | CUL4B, BRD4, CUL4A | VCAM1 1718/4885ALDH1A1 4616/4885MAPK1 3815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.