Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 6/20 | 0.71 |
| ▸ | ADK | P55263 | 3/20 | 0.66 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.60 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.53 |
| ▸ | DPP4 | P27487 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10060032 | 1.00 | METTL3 (0.71) | METTL3ADKPRMT5SLC29A1DPP4 | |
| SCHEMBL30597658 | 1.00 | METTL3 (0.71) | METTL3ADKPRMT5SLC29A1DPP4 | |
| SCHEMBL10079498 | 1.00 | METTL3 (0.71) | METTL3ADKPRMT5SLC29A1DPP4 | |
| SCHEMBL15948766 | 1.00 | METTL3 (0.71) | METTL3ADKPRMT5SLC29A1DPP4 | |
| SCHEMBL14429030 | 0.95 | ADK (0.67) | METTL3ADKPRMT5SLC29A1 | |
| SCHEMBL14429083 | 0.95 | ADK (0.67) | METTL3ADKPRMT5SLC29A1 | |
| SCHEMBL1738522 | 0.91 | ADK (0.69) | METTL3ADKPRMT5SLC29A1 | |
| Tubercidin SCHEMBL23351430 | 0.89 | ADK (0.82) | ADKSLC29A1DPP4 | |
| Tubercidin SCHEMBL20419325 | 0.89 | ADK (0.82) | ADKSLC29A1DPP4 | |
| Tubercidin SCHEMBL23982350 | 0.89 | ADK (0.82) | ADKSLC29A1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067640-A1 | PHENYL MALEIMIDE LINKER AGENTS | FIREFLY BIO, INC. | 2024-02-29 | — | — | US | disclosed |
| US-20240067640-A1 | PHENYL MALEIMIDE LINKER AGENTS | FIREFLY BIO, INC. | 2024-02-29 | — | — | US | disclosed |
| US-20240067640-A1 | PHENYL MALEIMIDE LINKER AGENTS | FIREFLY BIO, INC. | 2024-02-29 | — | — | US | disclosed |
| WO-2023173121-A1 | PHENYL MALEIMIDE LINKER AGENTS | FIREFLY BIO, INC. (US) | 2023-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240067640-A1 | PHENYL MALEIMIDE LINKER AGENTS | TPX2, H1-4, MAPT | METTL3 2305/4885ADK 3941/4885PRMT5 1112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.