SCHEMBL25413636

SCHEMBL25413636

O=C(O)C1CC(=O)N(c2ccccc2F)C1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.69
CASP1 P29466 1/20 0.68
CASP7 P55210 1/20 0.68
ALOX15 P16050 1/20 0.64
TSHR P16473 1/20 0.59
ALDH1A1 P00352 1/20 0.59
NOTUM Q6P988 1/20 0.55
KMT2A Q03164 3/20 0.53
MEN1 O00255 1/20 0.53
SCN3A Q9NY46 1/20 0.53
HPGD P15428 1/20 0.50
GRK2 P25098 1/20 0.49
CTDSP1 Q9GZU7 1/20 0.49
RECQL P46063 1/20 0.49
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA4 P22748 2/20 0.48
CA6 P23280 2/20 0.48
CA7 P43166 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11642625 0.86 MAPT (0.67) MAPTCASP1CASP7ALOX15TSHR
SCHEMBL21067417 0.83 MAPT (0.71) MAPTCASP1CASP7ALOX15TSHR
SCHEMBL27599117 0.83 MAPT (0.71) MAPTCASP1CASP7ALOX15TSHR
SCHEMBL2029995 0.83 TSHR (0.61) MAPTCASP1CASP7ALOX15TSHR
SCHEMBL20658870 0.82 MAPT (0.69) MAPTCASP1CASP7ALOX15TSHR
SCHEMBL11887760 0.82 MAPT (1.00) MAPTCASP1CASP7ALOX15ALDH1A1
SCHEMBL16111034 0.81 MAPT (0.60) MAPTCASP1CASP7ALOX15TSHR
SCHEMBL2560318 0.81 MAPT (0.68) MAPTCASP1CASP7ALOX15TSHR
SCHEMBL2555383 0.79 MAPT (0.66) MAPTCASP1CASP7ALOX15TSHR
SCHEMBL892508 0.79 CA12 (0.66) MAPTCASP1CASP7ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025122832-A1 IMIDAZOLE COMPOUNDS AND THEIR USE AS SODIUM CHANNEL INHIBITORS GENEP INC. (US) 2025-06-12 WO disclosed
WO-2023150508-A2 PLANT PRIMING COMPOSITIONS AND METHODS OF USE THEREOF ZERO GRAVITY SOLUTIONS, INC. (US) 2023-08-10 WO disclosed