SCHEMBL892508

SCHEMBL892508

O=C(O)C1CC(=O)N(c2ccccc2)C1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.66
CA1 P00915 1/20 0.66
CA2 P00918 1/20 0.66
CA4 P22748 1/20 0.66
CA6 P23280 1/20 0.66
CA7 P43166 1/20 0.66
CA9 Q16790 1/20 0.66
CA14 Q9ULX7 1/20 0.66
CA5B Q9Y2D0 1/20 0.66
MAPT P10636 1/20 0.65
RECQL P46063 1/20 0.64
TSHR P16473 2/20 0.63
CASP1 P29466 1/20 0.63
CASP7 P55210 1/20 0.63
ALDH1A1 P00352 1/20 0.61
GLA P06280 1/20 0.60
ALOX15 P16050 1/20 0.60
PTPN1 P18031 1/20 0.59
KMT2A Q03164 2/20 0.58
POLB P06746 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20116495 1.00 CA12 (0.66) CA12CA1CA2CA4CA6
SCHEMBL20676025 0.93 CA12 (0.74) CA12CA1CA2CA4CA6
SCHEMBL16131376 0.86 RAB9A (0.60) CA12CA1CA2CA4CA6
SCHEMBL20116623 0.86 ALDH1A1 (0.58) CA12CA1CA2CA4CA6
SCHEMBL13803643 0.86 ALDH1A1 (0.58) MAPTRECQLTSHRCASP1CASP7
SCHEMBL3365962 0.86 CA12 (0.67) CA12CA1CA2CA4CA6
SCHEMBL3367424 0.86 CA12 (0.67) CA12CA1CA2CA4CA6
SCHEMBL1776720 0.86 CA12 (0.67) CA12CA1CA2CA4CA6
SCHEMBL5451596 0.86 GLA (0.65) CA12CA1CA2CA4CA6
SCHEMBL7821361 0.86 CA12 (0.55) CA12CA1CA2CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4129573-A MAINTAINING TURF IN PBULIC AND TRAFFIC AREAS CIBA-GEIGY CORPORATION (US) 1978-12-12 US claimed
US-12637426-B2 1-cyano-pyrrolidine compounds as USP30 inhibitors MISSION THERAPEUTICS LIMITED (GB) 2026-05-26 US disclosed
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES Ananda Scientific, Inc. (US) 2025-06-19 US disclosed
EP-4308628-B1 ALKYD RESIN, COATING COMPOSITION, AND SUBSTRATE COATED WITH SUCH COATING COMPOSITON AKZO NOBEL COATINGS INT BV (NL) 2025-04-30 EP disclosed
US-12275723-B2 Compounds and uses thereof JANSSEN PHARMACEUTICA NV (BE) 2025-04-15 US disclosed
US-20240400546-A1 COMPOUNDS AND USES THEREOF JANSSEN PHARMACEUTICA NV (BE) 2024-12-05 US disclosed
US-20240300938-A1 COMPOUNDS AND USES THEREOF JANSSEN PHARMACEUTICA NV (BE) 2024-09-12 US disclosed
US-12054582-B2 Alkyd resin, coating composition, and substrate coated with such coating composition AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2024-08-06 US disclosed
CN-117098795-B Alkyd resin, coating composition and substrate coated with the coating composition 阿克佐 诺贝尔国际涂料股份有限公司 2024-07-19 CN disclosed
US-20240208955-A1 SMALL MOLECULE ANTAGONISTS FOR THE RELAXIN-3/RXFP3 SYSTEM RESEARCH TRIANGLE INSTITUTE 2024-06-27 US disclosed
WO-1997036900-A1 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 1997-10-09 WO disclosed
US-5108482-A Protect crep plant against phytotoxic action of herbicide; plant growth regulator CIBA-GEIGY CORPORATION (US) 1992-04-28 US disclosed
US-4987210-A COMPLEXING IODINE AND WATER-INSOLUBLE DRUGS TO MAKE THEM MORE SOLUBLE GAF CHEMICALS CORPORATION (US) 1991-01-22 US disclosed
US-4985521-A COPOLYMERS, COMPLEXES WITH WATER INSOLUBLE MOLECULES GAF CHEMICALS CORPORATION (US) 1991-01-15 US disclosed
US-4946967-A CHEMICAL INTERMEDIATES FOR HIGH MOLECULAR WEIGHT ACYCLIC ESTER OR AMIDE GAF CHEMICALS CORPORATION (US) 1990-08-07 US disclosed
WO-1990005131-A1 POLYMERIZABLE DERIVATIVES OF 5-OXO-PYRROLINE CARBOXYLIC ACID, POLYMERS THEREOF AND METHODS OF PREPARATION GAF CHEMICALS CORPORATION (US) 1990-05-17 WO disclosed
US-4129573-A MAINTAINING TURF IN PBULIC AND TRAFFIC AREAS CIBA-GEIGY CORPORATION (US) 1978-12-12 US disclosed
US-4129573-A MAINTAINING TURF IN PBULIC AND TRAFFIC AREAS CIBA-GEIGY CORPORATION (US) 1978-12-12 US disclosed
US-4129573-A MAINTAINING TURF IN PBULIC AND TRAFFIC AREAS CIBA-GEIGY CORPORATION (US) 1978-12-12 US disclosed
US-4013445-A 1-(Bis-trifluoromethylphenyl)-2-oxo-pyrrolidine-4-carboxylic acid derivatives, their production and their use as plant-growth regulators and herbicides CIBA-GEIGY CORPORATION (US) 1977-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240300938-A1 COMPOUNDS AND USES THEREOF NLN, ACHE, CLN6 CA12 1230/4885CA1 354/4885CA2 880/4885
US-20240400546-A1 COMPOUNDS AND USES THEREOF NLN, ACHE, CLN6 CA12 1230/4885CA1 354/4885CA2 880/4885
US-12275723-B2 Compounds and uses thereof NLN, ACHE, CLN6 CA12 1230/4885CA1 354/4885CA2 880/4885
US-20240208955-A1 SMALL MOLECULE ANTAGONISTS FOR THE RELAXIN-3/RXFP3 SYSTEM RXFP3, RXFP1, RXFP4 CA12 4230/4885CA1 4371/4885CA2 4061/4885
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES CNR2, CNR1, FAAH CA12 1845/4885CA1 1695/4885CA2 1050/4885
US-12637426-B2 1-cyano-pyrrolidine compounds as USP30 inhibitors USP30, USP1, USP10 CA12 2868/4885CA1 1479/4885CA2 2624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.