Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18470775 | 0.91 | GSK3A (0.44) | GSK3AGSK3BLMNAMGLLPKM | |
| SCHEMBL20677173 | 0.91 | GSK3A (0.44) | GSK3AGSK3BLMNAMGLLPKM | |
| SCHEMBL29398370 | 0.91 | GSK3A (0.44) | GSK3AGSK3BLMNAMGLLPKM | |
| SCHEMBL13541914 | 0.91 | LMNA (0.47) | GSK3AGSK3BLMNAMGLLPKM | |
| SCHEMBL24797572 | 0.87 | MGLL (0.43) | GSK3AGSK3BLMNAMGLLPKM | |
| SCHEMBL22311942 | 0.87 | MGLL (0.43) | GSK3AGSK3BLMNAMGLLPKM | |
| SCHEMBL27388123 | 0.87 | MGLL (0.43) | GSK3AGSK3BLMNAMGLLPKM | |
| SCHEMBL24797571 | 0.87 | MGLL (0.43) | GSK3AGSK3BLMNAMGLLPKM | |
| SCHEMBL24255821 | 0.87 | MGLL (0.43) | GSK3AGSK3BLMNAMGLLPKM | |
| SCHEMBL20338051 | 0.87 | LMNA (0.45) | GSK3AGSK3BLMNAMGLLPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129956-A1 | THIENOAZEPINE IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| EP-4313161-A1 | 2-AMINO-4-CARBOXAMIDE-BENZAZEPINE IMMUNOCONJUGATES, AND USES THEREOF | Bolt Biotherapeutics, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| WO-2023154302-A1 | MACROMOLECULE-SUPPORTED 8-SULFONYL-BENZAZEPINE COMPOUNDS AND THEIR USES | BOLT BIOTHERAPEUTICS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |