Nitrofurazone

Nitrofurazone

SCHEMBL25416

NC(=O)N/N=C/c1ccc([N+](=O)[O-])o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 1.00
ALDH1A1 P00352 5/20 1.00
CYP3A4 P08684 3/20 1.00
CYP1A2 P05177 3/20 1.00
KDM4E B2RXH2 3/20 1.00
SMN1; SMN2 Q16637 3/20 1.00
TP53 P04637 2/20 1.00
CYP2D6 P10635 1/20 1.00
HIF1A Q16665 1/20 1.00
PDE3A Q14432 1/20 1.00
SARM1 Q6SZW1 1/20 1.00
TDP1 Q9NUW8 3/20 0.74
HTT P42858 3/20 0.74
POLB P06746 5/20 0.71
L3MBTL1 Q9Y468 2/20 0.67
CASP6 P55212 1/20 0.67
MAPT P10636 7/20 0.66
MITF O75030 4/20 0.66
RAB9A P51151 3/20 0.66
MEN1 O00255 2/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrofurazone SCHEMBL25417 1.00 LMNA (1.00) LMNAALDH1A1CYP3A4CYP1A2KDM4E
Nitrofurazone SCHEMBL3681048 1.00 LMNA (1.00) LMNAALDH1A1CYP3A4CYP1A2KDM4E
Nitrofurazone SCHEMBL28198181 0.99 LMNA (0.97) LMNAALDH1A1CYP3A4CYP1A2KDM4E
Nitrofurazone SCHEMBL28285714 0.97 LMNA (0.94) LMNAALDH1A1CYP3A4CYP1A2KDM4E
Nitrofurazone SCHEMBL9928793 0.93 LMNA (0.87) LMNAALDH1A1CYP3A4CYP1A2KDM4E
Nitrofurazone SCHEMBL20775188 0.93 LMNA (0.87) LMNAALDH1A1CYP3A4CYP1A2KDM4E
Nitrofurazone SCHEMBL28246849 0.91 LMNA (0.83) LMNAALDH1A1CYP3A4CYP1A2KDM4E
Nitrofurazone SCHEMBL9054779 0.91 LMNA (0.83) LMNAALDH1A1CYP3A4CYP1A2KDM4E
Nitrofurazone SCHEMBL28871281 0.90 LMNA (0.81) LMNAALDH1A1CYP3A4CYP1A2KDM4E
Nifuraldezone SCHEMBL193103 0.89 LMNA (0.80) LMNAALDH1A1CYP3A4CYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 14938 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122011418-A One-dimensional ring chain manganese coordination polymer and preparation method and application thereof 青海民族大学 2026-05-12 CN claimed
EP-4255391-B1 LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2026-05-06 EP claimed
EP-4694929-A1 METHODS FOR TREATING CORNEAL INJURIES Lin, Sung-Jan (TW) 2026-02-18 EP claimed
US-20260000646-A1 Inhibition of Oral Microbe Biofilms THE UNIVERSITY OF TOLEDO (US) 2026-01-01 US claimed
EP-4630446-A1 ENGINEERED SWITCHES FOR IMMUNE CELL ACTIVITY AND METHODS OF USE THEREOF Dynamic Cell Therapies, Inc. (US) 2025-10-15 EP claimed
EP-4630043-A1 IMMUNE-ACTIVATING COMPLEXES Dynamic Cell Therapies, Inc. (US) 2025-10-15 EP claimed
US-20250222066-A1 COMPOSITIONS AND METHODS OF TREATING, PREVENTING OR INHIBITING A FACULTATIVE ANAEROBE INFECTION UNIVERSITY OF UTAH RESEARCH FOUNDATION 2025-07-10 US claimed
EP-4101437-B1 BACTERIOSTATIC COMPOSITION, PREPARATION METHOD THEREFOR AND USE THEREOF SHENZHEN EULIKAN BIOTECHNOLOGY CO LTD (CN) 2025-06-11 EP claimed
CN-120004253-A Preparation method of petal-shaped S, N-co-doped carbon nano-sheet loaded with hybrid magnetic nano-particles, and product and application thereof 湖南科技大学 2025-05-16 CN claimed
EP-4547023-A2 COMPOSITIONS AND METHODS OF TREATING, PREVENTING OR INHIBITING A FACULTATIVE ANAEROBE INFECTION University of Utah Research Foundation (US) 2025-05-07 EP claimed
EP-0138740-A2 Synthetic resin wound dressing and method of manufacturing ENQUAY PHARMACEUTICAL ASSOCIATES (US) 1985-04-24 EP claimed
EP-0126684-A2 Drug delivery system utilizing thermosetting gels MERCK & CO. INC. (US) 1984-11-28 EP claimed
EP-0122709-A1 Improvements in or relating to antibiotic or germicide layered implants ELI LILLY AND COMPANY (US) 1984-10-24 EP claimed
US-4478822-A Drug delivery system utilizing thermosetting gels MERCK & CO., INC. (US) 1984-10-23 US claimed
US-4474752-A DIAMINE MODIFIED POLYOXYETHYLENE-POLYOXYPROPYLENE COPOLYMER MERCK & CO., INC. (US) 1984-10-02 US claimed
US-4474751-A SUSTAINED RELEASE USING AN ALKYLENEDIAMINE-MODIFIED ETHYLENE OXIDE-PROPYLENE OXIDE COPOLYMER MERCK & CO., INC. (US) 1984-10-02 US claimed
US-4474753-A POLYETHERAMINE MERCK & CO., INC. (US) 1984-10-02 US claimed
EP-0055023-A2 Antiseptic containing adhesive composition E.R. Squibb & Sons, Inc. (US) 1982-06-30 EP claimed
US-4186184-A Selective administration of drug with ocular therapeutic system ALZA CORPORATION (US) 1980-01-29 US claimed
US-4024871-A POLYURETHANE ETHICON, INC. (US) 1977-05-24 US claimed