SCHEMBL25416745

SCHEMBL25416745

COC(=O)c1ccn2c(N)c(-c3ccc(OC)cc3OC)nc2c1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ TLR9 Q9NR96 6/20 0.42
▸ TLR7 Q9NYK1 5/20 0.42
▸ ADORA3 P0DMS8 4/20 0.42
▸ AKT1 P31749 1/20 0.41
▸ AKT2 P31751 1/20 0.41
▸ PLAU P00749 1/20 0.41
▸ KMT2A Q03164 2/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ GAA P10253 1/20 0.39
▸ ADRA1B P35368 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25416724 0.84 AKT1 (0.51) AKT1AKT2PLAUKMT2AGAA
SCHEMBL25417063 0.82 AKT1 (0.46) ADORA3AKT1AKT2PLAUGAA
SCHEMBL25416172 0.80 AKT1 (0.45) ADORA3AKT1AKT2PLAU
SCHEMBL17114242 0.77 AKT1 (0.60) AKT1AKT2PLAU
SCHEMBL25415193 0.76 AKT1 (0.52) AKT1AKT2PLAU
SCHEMBL25417148 0.75 AKT1 (0.61) AKT1AKT2PLAU
SCHEMBL31091940 0.72 AKT1 (0.39) AKT1AKT2PLAUKMT2AMEN1
SCHEMBL25252394 0.71 ADRA2B (0.45) ADORA3KMT2AMEN1
SCHEMBL25416128 0.71 AKT1 (0.47) TLR9AKT1AKT2PLAUKMT2A
SCHEMBL25415908 0.71 AKT1 (0.54) AKT1AKT2PLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260071117-A1 FUNABLE FLUORESCENT COMPOUNDS AND USES THEREOF UNIV ARIZONA (US) 2026-03-12 — — US disclosed
WO-2023081261-A1 TUNABLE FLUORESCENT COMPOUNDS AND USES THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2023-05-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071117-A1 FUNABLE FLUORESCENT COMPOUNDS AND USES THEREOF H1-3, NISCH, H1-2 TLR9 3980/4885TLR7 1283/4885ADORA3 288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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