SCHEMBL25417580

SCHEMBL25417580

CCN(CC)c1ccc(/C=N/c2c(-c3ccc(N(CC)CC)cc3)nc3cc(-c4ccncc4)ccn23)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 15/20 0.48
▸ ALDH1A1 P00352 14/20 0.48
▸ GAA P10253 10/20 0.48
▸ RAB9A P51151 5/20 0.48
▸ SMN1; SMN2 Q16637 5/20 0.48
▸ NPSR1 Q6W5P4 4/20 0.48
▸ NPC1 O15118 4/20 0.48
▸ MAPK1 P28482 2/20 0.48
▸ PKM P14618 1/20 0.48
▸ L3MBTL1 Q9Y468 1/20 0.48
▸ KDM4E B2RXH2 9/20 0.39
▸ LMNA P02545 3/20 0.39
▸ CYP1A2 P05177 2/20 0.39
▸ CYP3A4 P08684 2/20 0.39
▸ CYP2D6 P10635 2/20 0.39
▸ CYP2C19 P33261 2/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ TLR9 Q9NR96 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25417584 1.00 MAPT (0.48) MAPTALDH1A1GAARAB9ASMN1; SMN2
SCHEMBL25414769 0.79 ALDH1A1 (0.43) MAPTALDH1A1GAARAB9ASMN1; SMN2
SCHEMBL25169589 0.74 MAPT (0.48) MAPTALDH1A1GAARAB9ASMN1; SMN2
SCHEMBL11337596 0.69 MAPT (0.59) MAPTALDH1A1GAARAB9ASMN1; SMN2
SCHEMBL15591983 0.65 TERT (0.51) MAPTALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL9804049 0.62 MAPT (0.63) MAPTALDH1A1GAARAB9ASMN1; SMN2
SCHEMBL8573847 0.62 MAPT (0.63) MAPTALDH1A1GAARAB9ASMN1; SMN2
Bromide SCHEMBL29599463 0.60 MAPT (0.61) MAPTALDH1A1GAARAB9ASMN1; SMN2
SCHEMBL3971710 0.60 ALDH1A1 (0.67) MAPTALDH1A1GAARAB9ASMN1; SMN2
SCHEMBL25414210 0.60 ALDH1A1 (0.50) MAPTALDH1A1GAARAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260071117-A1 FUNABLE FLUORESCENT COMPOUNDS AND USES THEREOF UNIV ARIZONA (US) 2026-03-12 — — US disclosed
WO-2023081261-A1 TUNABLE FLUORESCENT COMPOUNDS AND USES THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2023-05-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071117-A1 FUNABLE FLUORESCENT COMPOUNDS AND USES THEREOF H1-3, NISCH, H1-2 MAPT 3635/4885ALDH1A1 2028/4885GAA 4639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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