Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9801767 | 0.87 | HDAC3 (0.51) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL1902999 | 0.86 | MAPK1 (0.55) | HTTHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL6122694 | 0.85 | HTT (0.44) | LTA4HHTTHDAC1HDAC2HDAC8 | |
| SCHEMBL7896669 | 0.81 | POLB (0.51) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL25209557 | 0.81 | TDP1 (0.46) | LTA4HHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL4228319 | 0.80 | NAAA (0.65) | HTTNAAABCHEMGLL | |
| SCHEMBL27157765 | 0.80 | NAAA (0.65) | HTTNAAABCHEMGLL | |
| SCHEMBL2906542 | 0.79 | TSHR (0.48) | KMT2AMAPK1BCHELMNA | |
| SCHEMBL5579337 | 0.77 | BCHE (0.45) | HTTHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL11280450 | 0.77 | BCHE (0.57) | HTTNAAABCHEACHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091441-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A TETRA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES | MERCK SHARP & DOHME LLC (US) | 2023-05-25 | — | — | WO | disclosed |