Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9801767 | 0.88 | HDAC3 (0.51) | BCHETDP1TSHRSLC6A2SLC6A3 | |
| SCHEMBL11280450 | 0.84 | BCHE (0.57) | BCHETSHRLMNAHTTNAAA | |
| SCHEMBL7896669 | 0.83 | POLB (0.51) | TDP1TSHRNAAAHDAC3HDAC4 | |
| SCHEMBL28543783 | 0.83 | TDP1 (0.64) | TDP1SLC6A2SLC6A3KMT2ANPC1 | |
| SCHEMBL11507378 | 0.82 | BCHE (0.39) | BCHETDP1TSHRSLC6A2SLC6A3 | |
| SCHEMBL9668519 | 0.81 | POLB (0.50) | TDP1TSHRSLC6A2SLC6A3KMT2A | |
| SCHEMBL27157765 | 0.81 | NAAA (0.65) | BCHEHTTNAAA | |
| SCHEMBL4228319 | 0.81 | NAAA (0.65) | BCHEHTTNAAA | |
| SCHEMBL1902999 | 0.81 | MAPK1 (0.55) | TSHRKMT2ALMNAHTTHDAC3 | |
| SCHEMBL28676424 | 0.80 | KDM4E (0.52) | TSHRKMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236756-B2 | HIV protease inhibitory compounds with ameliorated solubility and/or bioavailability; conjugates of therapeutic compound and a peptide wherein the conjugate is cleavable by dipeptidyl-peptidases | Consejo Superior de Investigaciones Clentificas (CSIC) (ES) | 2012-08-07 | — | — | US | disclosed |
| US-20070275900-A1 | Prodrugs Cleavable by Cd26 | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2007-11-29 | — | — | US | disclosed |
| EP-1620130-A1 | PRODRUGS CLEAVABLE BY CD26 | K.U. Leuven Research & Development (BE) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004098644-A1 | PRODRUGS CLEAVABLE BY CD26 | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2004-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275900-A1 | Prodrugs Cleavable by Cd26 | DPP4, DNPEP, DPP3 | BCHE 83/4885TDP1 1385/4885TSHR 2676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.