Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25423110 | 0.71 | — | — | |
| Iodide SCHEMBL30498493 | 0.61 | — | — | |
| SCHEMBL22252036 | 0.59 | HTR2A (0.35) | KDM4ENPC1ALDH1A1RAB9ATDP1 | |
| SCHEMBL29484542 | 0.58 | ADK (0.54) | RAB9A | |
| SCHEMBL23966903 | 0.57 | ADK (0.33) | — | |
| SCHEMBL29484474 | 0.57 | ADK (0.33) | — | |
| SCHEMBL25424287 | 0.56 | PKM (0.31) | — | |
| SCHEMBL29175942 | 0.54 | LRRK2 (0.35) | — | |
| SCHEMBL4783537 | 0.53 | CBLB (0.33) | — | |
| SCHEMBL21152790 | 0.53 | HSP90AA1 (0.39) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109954-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |