Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25423675 | 0.77 | HTR2A (0.46) | MAPTMEN1KMT2ANQO2MTNR1A | |
| SCHEMBL2533041 | 0.75 | GAA (0.67) | MAPTMEN1KMT2ARAB9AGAA | |
| SCHEMBL18509663 | 0.74 | GPR17 (0.53) | MAPTMEN1KMT2AGAALMNA | |
| SCHEMBL650217 | 0.72 | MAPT (0.86) | MAPTMEN1KMT2ARAB9AGAA | |
| SCHEMBL735125 | 0.70 | MAPT (1.00) | MAPTMEN1KMT2ARAB9AGAA | |
| SCHEMBL6675068 | 0.70 | ALDH1A1 (0.61) | MAPTMEN1KMT2ARAB9AGAA | |
| SCHEMBL2531516 | 0.67 | GAA (1.00) | MAPTMEN1KMT2ARAB9AGAA | |
| SCHEMBL8913853 | 0.67 | GAA (0.73) | MAPTMEN1KMT2ARAB9AGAA | |
| SCHEMBL2535334 | 0.67 | GAA (0.73) | MAPTMEN1KMT2ARAB9AGAA | |
| SCHEMBL18000215 | 0.67 | PTPRA (0.55) | MAPTMEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130070-A2 | CARBOLINE COMPOUNDS AND USE THEREOF | PTC THERAPEUTICS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |