Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 6/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 1.00 |
| ▸ | RAB9A | P51151 | 3/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.84 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21225808 | 0.89 | MAPT (0.90) | MAPTKMT2AMEN1RAB9AGAA | |
| SCHEMBL21837116 | 0.85 | MAPT (0.73) | MAPTKMT2AMEN1RAB9AGAA | |
| SCHEMBL2531516 | 0.84 | GAA (1.00) | MAPTKMT2AMEN1RAB9AGAA | |
| SCHEMBL8913853 | 0.84 | GAA (0.73) | MAPTKMT2AMEN1RAB9AGAA | |
| SCHEMBL650217 | 0.84 | MAPT (0.86) | MAPTKMT2AMEN1RAB9AGAA | |
| SCHEMBL2535334 | 0.84 | GAA (0.73) | MAPTKMT2AMEN1RAB9AGAA | |
| SCHEMBL9613799 | 0.83 | MAPT (0.75) | MAPTKMT2AMEN1RAB9AGAA | |
| SCHEMBL10523327 | 0.82 | MAPT (0.69) | MAPTKMT2AMEN1RAB9AGAA | |
| SCHEMBL733677 | 0.82 | RAB9A (0.69) | MAPTKMT2AMEN1RAB9AGAA | |
| SCHEMBL10554348 | 0.82 | GAA (0.70) | MAPTKMT2AMEN1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001517674-A | — | — | 2001-10-09 | — | — | JP | claimed |
| JP-2001517676-A | — | — | 2001-10-09 | — | — | JP | claimed |
| JP-2001517677-A | — | — | 2001-10-09 | — | — | JP | claimed |
| EP-1034180-A2 | LINKER NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME | Nanogen Recognomics GmbH (DE) | 2000-09-13 | — | — | EP | claimed |
| EP-1017703-A2 | PENTOPYRANOSYL NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME | Nanogen Recognomics GmbH (DE) | 2000-07-12 | — | — | EP | claimed |
| EP-1017704-A2 | USE OF A PENTOPYRANOSYL NUCLEOSIDE CONTAINING CONJUGATE FOR PRODUCING AN ARRAY | Nanogen Recognomics GmbH (DE) | 2000-07-12 | — | — | EP | claimed |
| WO-1999015542-A2 | LINKER NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-04-01 | — | — | WO | claimed |
| WO-1999015541-A2 | USE OF A PENTOPYRANOSYL NUCLEOSIDE FOR PRODUCING AN ELECTRONIC COMPONENT, AND CONJUGATES OF SAID PENTOPYRANOSYL NUCLEOSIDE | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-04-01 | — | — | WO | claimed |
| WO-1999015539-A2 | PENTOPYRANOSYL NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-04-01 | — | — | WO | claimed |
| CN-114989065-B | Preparation method of indole dimer compound | 中南大学 | 2023-09-29 | — | — | CN | disclosed |
| EP-3331988-B1 | CHEMICAL REPROGRAMMING TO GENERATE NEURONAL CELLS | THE J DAVID GLADSTONE INST A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J DAVID GLADSTONE (US) | 2023-09-20 | — | — | EP | disclosed |
| CN-114989065-A | Preparation method of indole dimer compound | 中南大学 | 2022-09-02 | — | — | CN | disclosed |
| US-9670305-B2 | Polyurethane dispersant and the method for its preparation | Wang, Zhijun (CN) | 2017-06-06 | — | — | US | disclosed |
| US-9670305-B2 | Polyurethane dispersant and the method for its preparation | Wang, Zhijun (CN) | 2017-06-06 | — | — | US | disclosed |
| WO-1999015540-A2 | METHOD FOR PRODUCING A PENTOPYRANOSYL NUCLEOSIDE | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 1999-04-01 | — | — | WO | disclosed |
| WO-1999015542-A2 | LINKER NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-04-01 | — | — | WO | disclosed |
| US-5849764-A | Antagonists of gonadotropin releasing hormone | MERCK & CO., INC. (US) | 1998-12-15 | — | — | US | disclosed |
| EP-0868178-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | Merck & Co., Inc. (US) | 1998-10-07 | — | — | EP | disclosed |
| US-5756507-A | TREATING SEX HORMONE RELATED DISORDERS | MERCK & CO., INC. (US) | 1998-05-26 | — | — | US | disclosed |
| WO-1997021435-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 1997-06-19 | — | — | WO | disclosed |