Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.32 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | MTR | Q99707 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.30 |
| ▸ | MERTK | Q12866 | 1/20 | 0.30 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.30 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25422609 | 0.94 | MAOA (0.34) | P2RX7MAOAHTR2AHTR2CHTR2B | |
| SCHEMBL25422666 | 0.88 | MAOA (0.35) | MAOAHTR2AHTR2CHTR2BCRBN | |
| SCHEMBL25422826 | 0.86 | HTR2A (0.38) | MAOAHTR2AHTR2CHTR2BCRBN | |
| SCHEMBL25422761 | 0.86 | MAOA (0.35) | MAOAHTR2AHTR2CHTR2BCRBN | |
| SCHEMBL25421860 | 0.84 | HTR2C (0.39) | MAOAHTR2AHTR2CHTR2BCRBN | |
| SCHEMBL25281394 | 0.83 | MAOA (0.38) | MAOAHTR2AHTR2CHTR2BCRBN | |
| Hydrochloric Acid SCHEMBL29099257 | 0.82 | MAOA (0.41) | MAOAHTR2AHTR2CHTR2BCRBN | |
| SCHEMBL25421672 | 0.81 | CRBN (0.36) | P2RX7CHRM3HTR2AHTR2CHTR2B | |
| SCHEMBL30458967 | 0.81 | PARP1 (0.42) | P2RX7CHRM3HTR2AHTR2CHTR2B | |
| SCHEMBL25421720 | 0.80 | HTR2A (0.39) | MAOAHTR2AHTR2CHTR2BCRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | claimed |