Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 11/20 | 0.41 |
| ▸ | HTR2C | P28335 | 10/20 | 0.41 |
| ▸ | HTR2A | P28223 | 9/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30459034 | 0.92 | PARP1 (0.42) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30459129 | 0.84 | HTR2B (0.44) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30459947 | 0.84 | HTR2B (0.46) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30458379 | 0.82 | HTR2B (0.44) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL25422934 | 0.81 | P2RX7 (0.39) | HTR2BHTR2CHTR2AP2RX7CHRM3 | |
| SCHEMBL30459711 | 0.81 | HTR2B (0.47) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30790468 | 0.80 | HTR2C (0.51) | PARP1HTR2BHTR2CHTR2A | |
| SCHEMBL30459712 | 0.80 | HTR2B (0.43) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30460171 | 0.79 | CRBN (0.55) | — | |
| SCHEMBL25646993 | 0.79 | CRBN (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | claimed |