Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.50 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.50 |
| ▸ | TPSAB1 | Q15661 | 6/20 | 0.42 |
| ▸ | TPSD1 | Q9BZJ3 | 6/20 | 0.42 |
| ▸ | TPSG1 | Q9NRR2 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255439 | 1.00 | DDB1 (0.50) | DDB1CRBNIKZF3TPSAB1TPSD1 | |
| SCHEMBL19262713 | 0.88 | DDB1 (0.47) | DDB1CRBNIKZF3TPSAB1TPSD1 | |
| SCHEMBL154944 | 0.86 | DDB1 (0.45) | DDB1CRBNIKZF3TPSAB1TPSD1 | |
| SCHEMBL154383 | 0.86 | DDB1 (0.45) | DDB1CRBNIKZF3TPSAB1TPSD1 | |
| SCHEMBL254664 | 0.82 | SLC6A5 (0.51) | — | |
| SCHEMBL157111 | 0.79 | DDB1 (0.39) | DDB1CRBNIKZF3NPC1RAB9A | |
| SCHEMBL156868 | 0.79 | DDB1 (0.39) | DDB1CRBNIKZF3NPC1RAB9A | |
| SCHEMBL13984525 | 0.78 | KDM4E (0.61) | NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL19262718 | 0.75 | DDB1 (0.46) | DDB1CRBNIKZF3MEN1NPC1 | |
| SCHEMBL19262604 | 0.75 | DDB1 (0.46) | DDB1CRBNIKZF3MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012031298-A2 | ETHYNYLBENZENE DERIVATIVES | DUKE UNIVERSITY (US) | 2012-03-08 | — | — | WO | disclosed |