SCHEMBL254664

SCHEMBL254664

Nc1ccc(OCc2ccc(C(=O)N[C@@H]3CCN(O)C3=O)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC6A5 Q9Y345 18/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL156868 0.83 DDB1 (0.39) SLC6A5
SCHEMBL157111 0.83 DDB1 (0.39) SLC6A5
SCHEMBL255439 0.82 DDB1 (0.50)
SCHEMBL254239 0.82 DDB1 (0.50)
SCHEMBL19262713 0.82 DDB1 (0.47)
SCHEMBL154944 0.80 DDB1 (0.45)
SCHEMBL154383 0.80 DDB1 (0.45)
SCHEMBL19262717 0.74 DDB1 (0.46)
SCHEMBL13984525 0.70 KDM4E (0.61)
SCHEMBL13244708 0.69 KDM4E (0.58)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012031298-A2 ETHYNYLBENZENE DERIVATIVES DUKE UNIVERSITY (US) 2012-03-08 WO disclosed